Product Description

Aceclofenac 100 mg, Paracetamol 325 mg & Chlorzoxazone 250 mg Tablets IP are a combination medication used for short-term relief of pain, inflammation, and muscle spasms associated with acute musculoskeletal disorders (e.g., strains, sprains, low back pain, or injuries). Myalgia (muscle pain) often results from overexertion, trauma, or conditions like arthritis, leading to stiffness, reduced mobility, and discomfort.

This tablet contains three active ingredients:

• Aceclofenac (a non-steroidal anti-inflammatory drug or NSAID) inhibits cyclooxygenase (COX-1 and COX-2) enzymes to reduce prostaglandin production, thereby alleviating pain and inflammation.

• Paracetamol (acetaminophen) (an analgesic and antipyretic), which acts centrally in the brain to inhibit COX and block pain signals, also reduces fever if present.

• Chlorzoxazone (a centrally acting muscle relaxant) depresses multisynaptic reflexes in the spinal cord and brainstem, leading to muscle relaxation without significant sedation.

Together, they provide synergistic effects for comprehensive relief from musculoskeletal pain and spasms. Take as prescribed by your doctor, typically 1 tablet 2-3 times daily for no more than 5-7 days. Common side effects include nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, tiredness, and sleepiness. These usually resolve but consult your doctor if persistent. Serious risks include gastrointestinal bleeding/ulcers (from aceclofenac), liver damage (from paracetamol overdose), or allergic reactions.

Uses

• Relief of acute musculoskeletal pain (e.g., back pain, strains, sprains)

• Reduction of inflammation and stiffness in soft tissue injuries

• Adjunctive treatment for muscle spasms associated with painful conditions

How it works

Aceclofenac 100 mg, Paracetamol 325 mg & Chlorzoxazone 250 mg Tablets IP combine an NSAID (aceclofenac), an analgesic (paracetamol), and a muscle relaxant (chlorzoxazone). Aceclofenac selectively inhibits COX-2 (more than COX-1) enzymes, reducing the synthesis of prostaglandins that mediate pain, fever, and inflammation at injury sites. Paracetamol primarily acts in the central nervous system to inhibit COX-3 or prostaglandin synthesis, providing analgesia and antipyresis without significant anti-inflammatory effects. Chlorzoxazone acts on the brainstem and spinal cord to inhibit polysynaptic reflexes, decreasing muscle tone and spasms while preserving motor function. This triple action targets pain, inflammation, and muscle rigidity for improved mobility.

Benefits

• Provides rapid relief from acute pain and inflammation in muscles and joints, allowing better daily function and recovery

• Chlorzoxazone component relaxes tense muscles, reducing spasms and stiffness without causing excessive weakness

• Paracetamol enhances pain control with minimal GI irritation compared to NSAIDs alone

• Effective for short-term use in conditions like sports injuries, low back pain, or post-trauma recovery, when combined with rest and physical therapy

• Lower risk of opioid dependence compared to stronger analgesics

How to use

• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.

• Take with food or milk to minimize stomach upset from the NSAID component.

• Use as directed (usually 2-3 times daily), not exceeding 7 days without medical review.

• Keep out of reach of children; do not self-medicate for chronic conditions.

Side Effects

Aceclofenac, Paracetamol, and Chlorzoxazone side effects

• Nausea or vomiting

• Heartburn or indigestion

• Stomach pain or abdominal discomfort

• Diarrhea

• Loss of appetite

• Tiredness or drowsiness

• Dizziness

• Headache

• Skin rash (rare, but stop use if it occurs)

Safety Advice

• Avoid alcohol while taking Aceclofenac 100 mg, Paracetamol 325 mg & Chlorzoxazone 250 mg Tablets IP, as it increases the risk of liver damage (from paracetamol), gastrointestinal bleeding (from aceclofenac), and enhanced sedation (from chlorzoxazone).

• Contraindicated in pregnancy (especially 3rd trimester due to risks like premature closure of ductus arteriosus from NSAIDs); consult your doctor if planning pregnancy or breastfeeding.

• Use with caution in patients with kidney/liver impairment (monitor function; lowest effective dose), heart disease (increased cardiovascular risk with NSAIDs), or asthma (possible exacerbation). Elderly patients are more prone to side effects like GI bleeding.

• Do not stop abruptly if symptoms improve, but consult your doctor for tapering if needed. Avoid driving or operating machinery if drowsy.

• Inform your doctor of all medications to prevent interactions (e.g., increased bleeding risk with anticoagulants, or liver toxicity with other paracetamol products).

Storage Conditions

• Store at temperatures below 30°C (86°F).

FAQs

What are Aceclofenac, paracetamol, and chlorzoxazone tablets used for?

Aceclofenac and paracetamol chlorzoxazone tablets are used to relieve musculoskeletal pain. It relieves pain by blocking the action of chemical messengers responsible for causing it.

Can I stop taking Aceclofenac, paracetamol & chlorzoxazone tablets if my symptoms improve before the prescribed period?

No, do not suddenly stop taking aceclofenac, paracetamol & chlorzoxazone tablets. Abrupt stopping of medication may worsen your condition. However, if you want to stop taking this medicine, consult your doctor.

Do aceclofenac, paracetamol, and chlorzoxazone tablets cause nausea?

Yes, Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet is known to cause nausea or vomiting. You should take Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet with milk or food to avoid the same. In case you are still experiencing excessive nausea while consuming Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet, speak with your doctor right away.

Does Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet cure Rheumatoid arthritis?

No, Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet does not cure rheumatoid arthritis; instead, it helps reduce the pain and inflammation caused by it for a short time, as Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet is an analgesic.

Is Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet safe for the kidneys?

Patients with mild to moderate kidney impairment should be closely monitored. The lowest effective dose should be given, and kidney function checked regularly. Effects on renal function are usually reversible on withdrawal of Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet.

Is Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet helpful in relieving stomach pain?

No, Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet is not recommended for stomach pain. This medication can increase the secretion of stomach acid and can cause stomach ulcers and bleeding. So, if you have any gastrointestinal ulcer, bleeding problem, or liver issue, speak to your doctor before using Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet.

What are the side effects of Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet?

The common side effects of Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet include nausea, vomiting, heartburn, stomach pain, diarrhoea, and loss of appetite. Consult your doctor if any of these side effects trouble you.

Can I take Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet for a toothache?

Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet is used to relieve pain and inflammation. Although it may help with certain types of pain, it is not usually the best option for a toothache. In such cases, a dental consultation is recommended to identify the cause and provide proper treatment.

Can I take my regular painkillers along with Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet?

Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet Tablet itself contains painkillers. Taking additional painkillers with Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg tablets can lead to overlapping side effects, increased risk of adverse reactions, and potential interactions. Please consult your doctor if you have severe pain so they can assess your situation and provide personalised guidance for safe and effective pain management.

What is Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet?

Aceclofenac 100mg, Paracetamol 325mg & Chlorzoxazone 250mg Tablet is a combination medication that contains three active ingredients: Aceclofenac, a pain killer; Paracetamol, a fever reducer and mild pain reliever; and Chlorzoxazone, a muscle relaxant. This medication primarily treats musculoskeletal pain, including conditions such as muscle strain, sprains, and injuries.