Product Description

Gabapentin 400mg & Nortriptyline 10mg Tablet is used for the management of neuropathic pain, a chronic condition caused by nerve damage. Symptoms of neuropathic pain include spontaneous or unprovoked pain, unpleasant sensations such as burning or stabbing, difficulty resting or sleeping, and pain triggered by normally non-painful stimuli.

This tablet contains two active ingredients: Gabapentin and Nortriptyline. Gabapentin binds to specific sites on voltage-gated calcium channels in nerve cells, reducing nerve excitability and relieving pain. Nortriptyline is a tricyclic antidepressant that increases the levels of serotonin and noradrenaline by blocking their reuptake, thereby reducing the transmission of pain signals in the brain.

Uses

Treatment and management of neuropathic pain

How it works

Gabapentin binds to voltage-gated calcium channels on nerve cells, decreasing the release of excitatory neurotransmitters and reducing nerve pain. Nortriptyline enhances the effects of serotonin and noradrenaline by inhibiting their reuptake, which helps block pain signal transmission in the central nervous system.

Benefits

• Provides effective relief from neuropathic pain

• Gabapentin also reduces the risk of seizures (antiepileptic effect)

• Nortriptyline improves mood and pain control by modulating neurotransmitter levels

• Combination therapy targets pain through complementary mechanisms for better symptom control

How to use

Take Gabapentin 400mg & Nortriptyline 10mg Tablet with or without food as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not chew, crush, or break it.

Side Effects

• Dizziness

• Sleepiness or drowsiness

• Fatigue or tiredness

• Headache

• Nausea

• Vomiting

• Blurred vision

• Dry mouth

Safety Advice

• Avoid alcohol consumption while taking this medication, as it may increase side effects such as dizziness and drowsiness.

• Consult your doctor if you have any concerns or pre-existing conditions. This medicine should be used only if the benefits outweigh the risks.

Storage Conditions

Store at a temperature below 86°F (30 °C).

FAQs

What is the use of Gabapentin 400mg & Nortriptyline 10mg Tablet?

It is used for the management of neuropathic pain.

How does Gabapentin 400mg & Nortriptyline 10mg Tablet work?

Gabapentin binds to voltage-gated calcium channels to relieve nerve pain, while Nortriptyline increases serotonin and noradrenaline levels to block pain signal transmission in the brain.

Can I stop taking Gabapentin 400mg & Nortriptyline 10mg Tablet if I feel well?

No, continue taking the medication as prescribed. Do not stop suddenly; consult your doctor for dose adjustments if needed.

Does Gabapentin 400mg & Nortriptyline 10mg Tablet cause dry mouth?

Yes, dry mouth is a possible side effect. Drinking water, sucking sugar-free candy, chewing sugar-free gum, or using saliva substitutes may help.

I have diabetes. Can I take a Gabapentin 400mg & Nortriptyline 10mg Tablet?

This medication is often used to treat diabetic neuropathy. However, consult your doctor before starting treatment.

How should I take a Gabapentin 400mg & Nortriptyline 10mg Tablet?

Swallow the tablet whole with water; do not crush or chew it.