Product Description

Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w Cream IP 15gm is a prescription topical medication used to treat hyperpigmentation disorders like melasma, as well as inflammatory skin conditions such as acne vulgaris or post-inflammatory hyperpigmentation. It combines a skin-lightening agent (Hydroquinone), a corticosteroid (Mometasone) to reduce inflammation, and a retinoid (Tretinoin) to promote skin cell turnover. This cream is effective for lightening dark patches on the skin, but it should be used under medical supervision to avoid potential side effects, such as irritation or photosensitivity.

Uses

Treatment of hyperpigmentation disorders, including:

• Melasma (dark patches on the skin, often due to sun exposure or hormones).

• Post-inflammatory hyperpigmentation (dark spots after acne or injury).

Management of inflammatory skin conditions, such as mild acne vulgaris, where redness and pigmentation are concerns.

It is not suitable for widespread use or conditions like fungal infections, as it does not address non-pigmentary issues.

How it works

Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w Cream IP 15gm combines three active ingredients for targeted therapy:

• Hydroquinone (2% w/w): Inhibits tyrosinase, an enzyme involved in melanin production, reducing dark pigmentation and lightening affected areas.

• Mometasone (0.1% w/w): A medium-potency corticosteroid that suppresses inflammation by inhibiting pro-inflammatory cytokines and reducing skin redness, swelling, and itching.

• Tretinoin (0.025% w/w): A retinoid that promotes epidermal cell turnover, unclogs pores, and enhances the penetration of other ingredients, aiding in skin renewal and reducing acne lesions.

Together, they address both pigmentation and inflammation, with effects visible in 4–6 weeks of consistent use.

Benefits

• Effective hyperpigmentation reduction: Lightens dark spots by 50–70% in clinical trials (e.g., as reported in the Journal of the American Academy of Dermatology), thereby improving skin tone and texture.

• Anti-inflammatory relief: Reduces redness and irritation, making it suitable for combination skin issues like acne with post-inflammatory marks.

• Comprehensive skin care: Promotes faster healing and prevents recurrence, with studies showing improved patient satisfaction due to visible results.

How to use

Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w Cream IP 15gm is for external use only. Wash and dry the affected area before application. Apply a thin layer once or twice daily, as directed by your doctor, and gently rub it in. Use sunscreen during the day, as Tretinoin increases sun sensitivity. Avoid contact with eyes, mouth, or broken skin; if contact occurs, rinse thoroughly. Do not use on large areas or for extended periods without medical advice. If you miss a dose, apply it as soon as possible, but skip if it's near the next one—do not double up.

Side Effects

Common side effects (usually mild and transient):

• Skin reactions: Redness, irritation, dryness, or peeling at the application site.

• Other: Itching, burning sensation, or increased sun sensitivity.

Rare but serious side effects may include allergic reactions, skin discoloration, or thinning of the skin. Discontinue use and consult a doctor if severe symptoms occur.

Safety Advice

• Alcohol Interaction: No significant interaction, but alcohol can exacerbate skin irritation; consult your doctor.

• Pregnancy and Breastfeeding: Classified as Pregnancy Category C (animal studies show risks, and human data are limited), so use only if the benefits outweigh the risks. It may cause fetal harm; consult your doctor if pregnant or breastfeeding, as absorption is minimal but possible.

• Other Precautions: Use with caution in patients with eczema, rosacea, or sun-damaged skin, as it can worsen these conditions. Avoid prolonged use to prevent skin atrophy or resistance. Not recommended for children or those with viral/fungal infections. Inform your doctor of all medications to avoid interactions (e.g., with other retinoids or steroids). Apply sunscreen daily, as it increases UV sensitivity. Regular skin checks are advised to monitor for irritation.

• Lifestyle Advice: Use gentle skincare products, avoid sun exposure, and follow up with your doctor for re-evaluation.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What are the instructions for the storage and disposal of Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w  Cream?

Store this medicine in its original packet or container, securely closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Ensure that pets, children, and others do not ingest it.

How to use Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w Cream?

Follow the directions given by the doctor. Apply the medicine thinly and in sufficient quantity to cover the affected areas. Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w  Cream is usually applied two or three times a day to the affected areas of skin.

Will Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w  Cream be more effective if taken more than prescribed?

No, Hydroquinone 2%w/w, Mometasone 0.1%w/w & Tretinoin 0.025%w/w  Cream will not be more effective if overused. Overusing the medicine can result in too much medicine being absorbed into the body. This may cause skin thinning or weakening and other serious side effects. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.