{"product_id":"hydroxychloroquine-tablets-200mg","title":"Hydroxychloroquine Tablets IP 200 mg","description":"\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eHydroxychloroquine Tablets IP 200 mg (hydroxychloroquine sulfate) is a 4-aminoquinoline derivative related to chloroquine, with antimalarial, anti-inflammatory, and immunomodulatory properties. It is used to prevent and treat uncomplicated malaria caused by Plasmodium species sensitive to chloroquine (e.g., P. vivax, P. ovale, P. malariae, and chloroquine-sensitive P. falciparum). For autoimmune conditions, it acts as a disease-modifying antirheumatic drug (DMARD) to reduce immune overactivity in rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), systemic lupus erythematosus (SLE), and porphyria cutanea tarda (PCT). It works by interfering with parasite metabolism in malaria and modulating immune responses in autoimmune diseases.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eUses\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003ePrevention and treatment of malaria in chloroquine-sensitive regions\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eManagement of rheumatoid arthritis (RA)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eTreatment of juvenile idiopathic arthritis (JIA)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eControl of systemic lupus erythematosus (SLE) and its flares\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eTreatment of porphyria cutanea tarda (PCT)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow it works\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eHydroxychloroquine's mechanism varies by indication:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cstrong\u003eFor Malaria:\u003c\/strong\u003e Accumulates in the parasite's food vacuole, raising pH and inhibiting heme polymerization (a process where the parasite digests hemoglobin for survival). This leads to toxic heme buildup, killing the parasite.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cstrong\u003eFor Autoimmune Diseases:\u003c\/strong\u003e As a DMARD, it inhibits lysosomal acidification in immune cells, reducing antigen presentation, cytokine production (e.g., IL-1, TNF-α), and Toll-like receptor signaling. This dampens overactive immune responses, decreasing inflammation and autoantibody formation. Effects are slow-acting, often taking weeks to months.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eReduces joint pain, swelling, and stiffness in RA and JIA by modulating immune activity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eDecreases frequency and severity of SLE flares, potentially protecting against organ damage (e.g., kidneys in lupus nephritis).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eImproves skin and photosensitivity symptoms in SLE and PCT.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eMay lower thrombosis risk in SLE patients and improve metabolic parameters (e.g., lipid profiles, blood glucose control).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eAssociated with better long-term survival in SLE based on observational studies.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eEffective for malaria prophylaxis and treatment in sensitive strains, with a favorable safety profile compared to chloroquine.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow to use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eTake exactly as prescribed; dosage varies by condition (e.g., 200–400 mg daily for RA\/SLE; 400 mg weekly for malaria prevention).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eSwallow tablets whole with water, preferably with food or milk to reduce gastrointestinal upset and improve absorption. Do not crush, chew, or break due to bitter taste and potential reduced efficacy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eFor chronic conditions (RA, SLE), take once or twice daily on a consistent schedule. For malaria prevention, take weekly on the same day, starting 1–2 weeks before travel and continuing 4 weeks after.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eComplete the full course for malaria treatment; do not stop abruptly for autoimmune conditions, as symptoms may recur.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eRegular monitoring (e.g., eye exams, blood tests) is required during long-term use.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eCommon side effects:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eGastrointestinal: nausea, vomiting, diarrhea, stomach pain, loss of appetite\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eNeurological: headache, dizziness, irritability, nervousness\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eDermatological: rash, itching, hair loss (reversible)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eSafety Advice\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eUndergo baseline and annual eye exams (including visual field testing) due to retinopathy risk, especially with doses \u0026gt;5 mg\/kg\/day or use \u0026gt;5 years.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eMonitor heart function with ECG if you have a cardiac history or risk factors (e.g., QT prolongation).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eInform your doctor if pregnant, breastfeeding, or planning pregnancy (Category C; benefits often outweigh risks in autoimmune diseases, but use the lowest effective dose). Small amounts pass into breast milk; generally safe, but monitor the infant.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eAvoid in patients with retinopathy, maculopathy, or hypersensitivity. Use caution with liver\/kidney disease, G6PD deficiency, or psoriasis (may worsen).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eAvoid alcohol and antacids (aluminum\/magnesium) within 4 hours of dosing, as they reduce absorption.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003eInform your doctor of all medications (e.g., digoxin, diabetes drugs) to avoid interactions. Do not self-medicate for malaria without confirmation of sensitivity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eStore at a temperature below 30°C (86°F) in a cool, dry place.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eFAQs\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eWhat is the difference between hydroxychloroquine and chloroquine?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eBoth are antimalarials, but hydroxychloroquine has a longer half-life, better tolerability, and lower retinopathy risk, making it preferred for long-term autoimmune use.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow long does it take for hydroxychloroquine to work for autoimmune conditions?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eIt is slow-acting; initial improvements in RA\/SLE may occur in 6–12 weeks, with full benefits up to 6 months.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhy are regular eye exams necessary?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eLong-term use can cause irreversible retinopathy; baseline and annual exams (e.g., funduscopy, visual fields) allow early detection.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eCan hydroxychloroquine cause heart problems?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eYes, it may prolong the QT interval or worsen heart failure. ECG monitoring is recommended for at-risk patients.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eDoes it affect blood sugar?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eYes, it can cause hypoglycemia, especially in diabetics. Monitor blood sugar closely and report symptoms like sweating or confusion.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eCan you take antacids with hydroxychloroquine?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eNo, aluminum- or magnesium-containing antacids reduce absorption. Take them at least 4 hours apart.\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eDoes it interact with other medicines?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003eYes, with drugs like digoxin (increased levels), insulin\/oral hypoglycemics (enhanced effects), and others. Always disclose the full medication list.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs it safe during pregnancy or breastfeeding?\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eFor autoimmune conditions, benefits often outweigh risks (Category C); continue at the lowest dose if needed. Safe in breastfeeding with monitoring, as minimal amounts enter milk. Consult your doctor.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Generic Remedy","offers":[{"title":"Hydroxychloroquine Tablets IP 200 mg","offer_id":43299461628013,"sku":"GR462","price":45.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0619\/7349\/5917\/files\/Box_of_Hydroxychloroquine_tablets_200_mg_front_image.png?v=1772176454","url":"https:\/\/www.genericremedy.com\/products\/hydroxychloroquine-tablets-200mg","provider":"Generic Remedy","version":"1.0","type":"link"}