Product Description

Glimepiride IP 1 mg & Metformin 500 mg PR Tablets are a combination of two antidiabetic drugs used to treat type 2 diabetes mellitus, especially in patients whose blood sugar levels are not adequately controlled by diet and exercise alone. Type 2 diabetes is a chronic condition where the body either does not produce enough insulin or cannot use insulin effectively due to insulin resistance.

• Glimepiride stimulates pancreatic beta cells to release insulin, helping lower blood sugar levels.

• Metformin reduces glucose production in the liver, slows sugar absorption from the intestines, and improves insulin sensitivity in muscle cells, allowing better glucose uptake from the blood.

Take this medication exactly as prescribed by your doctor. It is important to continue treatment for as long as recommended. Common side effects include stomach pain, nausea, diarrhea, vomiting, headache, and a metallic taste. Most side effects are mild and resolve on their own, but if they persist or worsen, consult your doctor.

Avoid alcohol while taking this medication, as it increases the risk of lactic acidosis (a dangerous buildup of lactic acid). Do not breastfeed while on this medication, and inform your doctor if you are pregnant or planning pregnancy.

Uses

Treatment of type 2 diabetes mellitus

How it works

Glimepiride stimulates insulin secretion from the pancreas, lowering blood glucose. Metformin decreases hepatic glucose production, delays intestinal glucose absorption, and enhances peripheral glucose uptake by improving insulin sensitivity.

Benefits

• Helps control blood sugar levels in type 2 diabetes

• Combines two complementary mechanisms for better glucose control

• May reduce the risk of diabetes-related complications when combined with diet and exercise

How to use

Take the tablet whole with a full glass of water. Do not crush, break, or chew. Follow your doctor’s instructions regarding dosage and timing.

Side Effects

• Stomach pain

• Nausea

• Diarrhea

• Vomiting

• Headache

• Metallic taste

Safety Advice

• Avoid alcohol to reduce the risk of lactic acidosis.

• Not recommended during pregnancy or breastfeeding. Consult your doctor if pregnant or planning pregnancy.

• Use with caution if you have kidney or liver disease; your doctor may adjust the dose.

• Monitor blood glucose regularly.

• Carry a source of fast-acting sugar to treat hypoglycemia.

• Inform your doctor before surgery or medical tests.

Storage Conditions

• Store at room temperature (20–25°C / 68–77°F)

FAQs

What is the use of Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

Glimepiride IP 1 mg & Metformin 500 mg Tablet PR is indicated in the treatment of type 2 diabetes mellitus.

How does Glimepiride IP 1 mg & Metformin 500 mg Tablet PR work?

Glimepiride IP 1 mg & Metformin 500 mg Tablet PR works by decreasing the amount of glucose absorbed from the food and the amount of glucose made by the liver. It helps the pancreas to produce insulin and helps the body use insulin efficiently.

Does Glimepiride IP 1 mg & Metformin 500 mg Tablet PR cause low blood sugar levels?

Glimepiride IP 1 mg & Metformin 500 mg Tablet PR may increase the risk of low blood sugar levels, especially with alcohol intake, exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure, such as dizziness, nausea, light-headedness, dehydration, or fainting, please consult a doctor.

What is the difference between type 1 diabetes and type 2 diabetes?

In type 1 diabetes, the body doesn't produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completely. In type 2 diabetes, though islet cells are working, the body doesn't respond to insulin as the body becomes resistant to insulin.

Can I stop taking Glimepiride IP 1 mg & Metformin 500 mg Tablet PR on my own?

You are not recommended to stop taking Glimepiride IP 1 mg & Metformin 500 mg Tablet PR on your own, as discontinuing Glimepiride IP 1 mg & Metformin 500 mg Tablet PR suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glimepiride IP 1 mg & Metformin 500 mg Tablet PR, please consult your doctor so that alternative medicine may be prescribed.

Can I take Glimepiride IP 1 mg & Metformin 500 mg Tablet PR with phenytoin?

You are not recommended to take Glimepiride IP 1 mg & Metformin 500 mg Tablet PR with phenytoin, as it may reduce the effect of Glimepiride IP 1 mg & Metformin 500 mg Tablet PR and increase blood sugar levels. However, please consult a doctor before using Glimepiride IP 1 mg & Metformin 500 mg Tablet PR with other medicines.

What diet should I follow?

Include a diet rich in fruits, vegetables, and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.

What should I do to avoid being a diabetic patient?

Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice, and starchy vegetables.

For how long do I need to take Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

You are advised to take Glimepiride IP 1 mg & Metformin 500 mg Tablet PR for the duration recommended by the doctor.

What are the recommended storage conditions for Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

Store Glimepiride IP 1 mg & Metformin 500 mg Tablet PR at room temperature, in a dry place. Keep out of sight and reach of children.

Can the use of Glimepiride IP 1 mg & Metformin 500 mg Tablet PR cause lactic acidosis?

Glimepiride IP 1 mg & Metformin 500 mg Tablet PR may cause lactic acidosis (build-up of lactic acid in the blood). Consult the doctor if you notice symptoms of lactic acidosis, like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.

What is Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

Glimepiride IP 1 mg & Metformin 500 mg Tablet PR is an anti-diabetic medicine used to treat type 2 diabetes mellitus, also known as non-insulin-dependent diabetes mellitus.

What are the possible side effects of Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

Side effects of Glimepiride IP 1 mg & Metformin 500 mg Tablet PR are stomach pain, nausea, diarrhoea, vomiting, headache, or metallic taste. Most of these side effects may not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Can the use of Glimepiride IP 1 mg & Metformin 500 mg Tablet PR lead to Vitamin B12 deficiency?

Long-term use of Glimepiride IP 1 mg & Metformin 500 mg Tablet PR may lead to vitamin B12 deficiency. Regular monitoring of vitamin B12 levels is recommended.

Is it safe to take alcohol while I am also taking Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

You are recommended to avoid the consumption of alcohol with Glimepiride IP 1 mg & Metformin 500 mg Tablet PR, as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

How should I take Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

Glimepiride IP 1 mg & Metformin 500 mg Tablet PR should be swallowed as a whole with water; do not crush, break, or chew it.

What precautions should I take while using Glimepiride IP 1 mg & Metformin 500 mg Tablet PR?

Regularly monitor blood glucose levels. Have your meals regularly and never miss a meal. Always carry a source of sugar and consume it if you experience low blood sugar. If you are due to undergo any tests or surgery, inform the doctor that you are taking Glimepiride IP 1 mg & Metformin 500 mg Tablet PR. Avoid drinking alcohol.