Product Description

Montelukast 10 mg & Fexofenadine Hydrochloride 120 mg Tablets IP belong to a class of medications called anti-allergics, primarily used to manage symptoms of seasonal or perennial allergic rhinitis (hay fever) and chronic urticaria (hives). Allergies occur when the immune system overreacts to harmless substances (allergens) like pollen, dust mites, pet dander, or certain foods, triggering symptoms such as sneezing, runny or stuffy nose, itchy/watery eyes, coughing, and nasal congestion. This combination may also help prevent asthma symptoms in patients with allergic triggers, but it is not for acute asthma attacks.

This tablet contains two active ingredients:

• Montelukast (a leukotriene receptor antagonist) blocks leukotrienes—inflammatory chemicals released in the airways that cause swelling, mucus production, and bronchoconstriction.

• Fexofenadine hydrochloride (a second-generation antihistamine), which selectively blocks H1 histamine receptors to reduce allergic responses like itching, sneezing, and a runny nose without significant central nervous system effects (non-sedating).

Together, they provide comprehensive relief from upper and lower respiratory allergy symptoms. Take as prescribed by your doctor, usually once daily. Common side effects include headache, drowsiness (mild), nausea, diarrhea, and skin rash, which typically resolve on their own. Consult your doctor if symptoms persist or worsen.

Inform your doctor before use if you have allergies to any components, phenylketonuria (for chewable forms, if applicable), liver/kidney impairment, or a history of psychiatric issues (e.g., montelukast may rarely cause mood changes). Not recommended for acute asthma attacks—use a rescue inhaler instead. Avoid if pregnant (FDA category B for montelukast, C for fexofenadine; use only if benefits outweigh risks) or breastfeeding (both may pass into milk). Regular monitoring may be needed for long-term use in asthmatics.

Uses

• Relief of allergic rhinitis symptoms (sneezing, runny/stuffy nose, itchy/watery eyes)

• Management of chronic idiopathic urticaria (hives and itching)

• Prevention of exercise-induced bronchoconstriction or allergic asthma symptoms (adjunct therapy)

How it works

Montelukast 10 mg & Fexofenadine Hydrochloride 120 mg Tablets IP combine a leukotriene antagonist (montelukast) and an antihistamine (fexofenadine). Montelukast selectively blocks cysteinyl leukotriene receptors (CysLT1) in the airways, preventing leukotriene-mediated inflammation, mucus secretion, and airway narrowing, which reduces swelling and improves breathing. Fexofenadine competitively antagonizes peripheral H1 histamine receptors, inhibiting the release of histamine-induced effects like vasodilation, itching, and nasal congestion. This dual mechanism targets multiple allergic pathways for faster and more complete symptom relief.

Benefits

• Provides rapid and sustained relief from allergy symptoms like sneezing, nasal congestion, runny nose, watery/itchy eyes, and throat irritation

• Reduces inflammation in the airways, helping prevent asthma exacerbations triggered by allergens (e.g., pollen or dust)

• Fexofenadine offers non-sedating antihistamine action, allowing daytime use without impairing alertness

• Montelukast improves long-term control of allergic asthma or rhinitis, reducing the need for other medications

• Suitable for seasonal (e.g., hay fever) or year-round allergies, improving quality of life and sleep

How to use

• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.

• Take once daily, with or without food, preferably in the evening (for montelukast's optimal effect on nighttime symptoms).

• Avoid taking fexofenadine component with fruit juices (e.g., orange, grapefruit, apple), as they can reduce absorption by up to 30%.

• For best results, use consistently, even if symptoms improve; do not exceed the prescribed dose.

Side Effects

Montelukast and Fexofenadine Hydrochloride Tablets side effects

• Headache

• Drowsiness (mild, less common with fexofenadine)

• Nausea or vomiting

• Diarrhea

• Dizziness

• Skin rash or itching

• Abdominal pain

• Fever (rare)

Safety Advice

• Limit or avoid alcohol while taking Montelukast 10 mg & Fexofenadine Hydrochloride 120 mg Tablets IP, as it may enhance mild drowsiness or dizziness. Consult your doctor for personalized advice.

• Use during pregnancy only if clearly needed (benefits must outweigh potential risks to the fetus); not well-studied in large trials. Avoid or use caution during breastfeeding, as both drugs may be excreted in breast milk and affect the infant.

• Safe for most adults and children over 12 years (for this strength); consult a pediatrician for younger patients.

• Monitor for neuropsychiatric effects (e.g., mood changes, vivid dreams) with montelukast, especially in those with a mental health history—report immediately.

• Inform your doctor of all medications to avoid interactions (e.g., with rifampin or erythromycin, which may alter levels). Do not use for acute allergies or asthma attacks.

Storage Conditions

• Store at temperatures below 30°C (86°F).

FAQs

What is the use of Montelukast & Fexofenadine Hydrochloride Tablets?

They are used to treat and prevent allergic symptoms such as sneezing, runny/stuffy nose, congestion, watery/itchy eyes, and related asthma triggers.

What foods are to be avoided while taking Montelukast and Fexofenadine Hydrochloride Tablets?

Avoid fruit juices like orange, grapefruit, or apple juice, as they can decrease fexofenadine absorption and reduce effectiveness. Take it with water instead.

Are Montelukast & Fexofenadine Hydrochloride Tablets used to treat an asthma attack?

No, they are for prevention and long-term management of allergic asthma or rhinitis, not acute attacks. Always carry a rescue inhaler (e.g., albuterol) for sudden symptoms and seek emergency care if needed.

Do Montelukast 10mg & Fexofenadine Hydrochloride 120mg Tablets IP cause drowsiness?

Fexofenadine is generally non-sedating, but the combination may cause mild drowsiness in some people. Avoid driving or operating machinery if you feel dizzy or sleepy.

What are the consequences of taking more than the prescribed dose of Montelukast 10 mg and Fexofenadine Hydrochloride 120 mg Tablets IP?

Overdose may cause symptoms like headache, drowsiness, thirst, dry mouth, nausea, vomiting, dizziness, or heart palpitations. Seek immediate medical help; do not exceed the dose without advice.