{"product_id":"ranolazine-1000mg","title":"Ranolazine Sustained Release 1000mg Tablet IP","description":"\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eRanolazine Sustained Release Tablets 1000mg IP \u003c\/span\u003e\u003cspan\u003eis used alone or in combination with other medicines to treat chronic stable angina pectoris. Angina pectoris is chest discomfort or pain that occurs when the heart muscle does not receive enough oxygen-rich blood, often due to coronary artery disease (CAD) or blockage of the heart’s arteries. This medicine helps prevent angina attacks by improving the heart’s efficiency and oxygen utilization.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe active ingredient, Ranolazine, reduces the late sodium current in heart muscle cells. This action decreases intracellular calcium overload by limiting sodium-dependent calcium influx through sodium-calcium exchange channels. By reducing calcium entry, Ranolazine helps the heart muscle relax, improving blood flow and relieving angina symptoms.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eYour doctor will determine the appropriate dosage based on your medical condition. Common side effects include constipation, dizziness, headache, and nausea. Most side effects are mild and tend to resolve over time. If side effects persist or worsen, consult your doctor.\u003c\/span\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eUses\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eTreatment of chronic stable angina pectoris\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eUsed as an add-on therapy when angina is not adequately controlled by beta-blockers or calcium channel blockers, or when these drugs are contraindicated\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow it works\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eRanolazine works by selectively inhibiting the late phase of the inward sodium current in cardiac cells. This reduces calcium overload in the heart muscle, improving myocardial relaxation and oxygen efficiency without significantly affecting heart rate or blood pressure. This mechanism differs from other anti-anginal drugs like beta-blockers and calcium channel blockers.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eReduces the frequency and severity of angina attacks\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDecreases the need for nitroglycerin use for symptom relief\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eImproves exercise tolerance and quality of life in patients with chronic stable angina\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eEffective as an add-on therapy when other anti-anginal medications are insufficient or contraindicated\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDoes not significantly lower heart rate or blood pressure, making it suitable for patients who cannot tolerate such effects\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow to use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eTake Ranolazine Sustained Release Tablets 1000mg exactly as prescribed by your doctor. Swallow the tablet whole with water. It can be taken with or without food. Do not crush, chew, or break the tablet. Usually taken twice daily at consistent times.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDizziness\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eHeadache\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eConstipation\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eNausea\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eVomiting\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eWeakness (asthenia)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eSafety Advice\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eAvoid or limit alcohol consumption while taking Ranolazine, as it may increase side effects such as dizziness.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eInform your doctor if you have liver or kidney problems before starting treatment.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eRanolazine may prolong the QT interval on an ECG, which can lead to serious heart rhythm disturbances; regular monitoring may be required.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDo not take Ranolazine if you have severe liver impairment or severe kidney disease.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eAvoid grapefruit and grapefruit juice, as they can increase Ranolazine blood levels and risk of side effects.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eInform your doctor about all medications you are taking, especially strong CYP3A inhibitors or inducers, P-glycoprotein inhibitors, and certain cholesterol-lowering drugs, as these can interact with Ranolazine.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eStore at a temperature below 86°F (30 °C).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eFAQs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow does Ranolazine work?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eRanolazine inhibits the late sodium current in heart muscle cells, reducing calcium overload and improving heart muscle relaxation and oxygen efficiency without significantly affecting heart rate or blood pressure.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow should this medication be taken?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSwallow the Sustained-release tablets whole with water, with or without food, usually twice daily at consistent times. Do not crush or chew.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhat should be done if a dose is missed?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eTake the next dose at the scheduled time. Do not double the dose to make up for a missed one.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eCan Ranolazine be stopped when symptoms improve?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eConsult your doctor before stopping Ranolazine, as sudden discontinuation may worsen angina symptoms.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhat are the common side effects?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eDizziness, headache, constipation, nausea, and weakness.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhat are the serious side effects of Ranolazine?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eRarely, Ranolazine can cause heart rhythm changes (prolonged QT interval), kidney problems in severe cases, or allergic reactions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWho should not take Ranolazine?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePatients with severe liver impairment, severe kidney disease, or those taking strong CYP3A inhibitors or inducers should avoid Ranolazine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhat other medications should be avoided or used with caution?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAvoid strong CYP3A inhibitors (e.g., ketoconazole, clarithromycin), inducers (e.g., rifampin), and certain cholesterol medications (e.g., simvastatin) without medical advice.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eShould any food or beverages be avoided?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eDo not consume grapefruit or grapefruit juice, as it can increase the level of Ranolazine in your blood and raise the risk of side effects. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eCan alcohol be consumed while taking Ranolazine?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eLimit or avoid alcohol, as it can increase side effects like dizziness. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eCan Ranolazine be used during pregnancy or breastfeeding?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe safety during pregnancy and breastfeeding is not fully known. Discuss the potential benefits and risks with a doctor if you are pregnant, planning pregnancy, or breastfeeding. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Generic Remedy","offers":[{"title":"Ranolazine Sustained Release 1000 mg Tablet IP","offer_id":42697731571821,"sku":"GR262","price":98.0,"currency_code":"INR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0619\/7349\/5917\/files\/ranolazine_sustained_release_tablets_1000mg.png?v=1772259570","url":"https:\/\/www.genericremedy.com\/products\/ranolazine-1000mg","provider":"Generic Remedy","version":"1.0","type":"link"}