{"product_id":"sitagliptin-phosphate-50mg-metformin-hydrochloride-1000mg","title":"Sitagliptin 50mg \u0026 Metformin Hydrochloride 1000mg Tablets IP","description":"\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets IP \u003c\/span\u003e\u003cspan\u003ebelong to the class of anti-diabetic agents used to treat Type 2 diabetes mellitus. Type 2 diabetes is a condition in which either the body stops producing enough insulin (the hormone that helps decrease blood sugar levels) or there is resistance to the action of insulin. As a result, the body produces large amounts of insulin, but it cannot effectively act on the organs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets is a combination drug containing Sitagliptin and Metformin. Metformin reduces the release of stored sugar (glucose) from the liver, decreases sugar absorption from the gastrointestinal tract, and improves the body’s sensitivity to insulin, enhancing glucose utilization. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases the levels of incretin hormones, which stimulate the pancreas to release more insulin and reduce glucagon secretion, helping regulate blood sugar levels. Together, Sitagliptin Phosphate 50 mg \u0026amp; Metformin Hydrochloride 1000 mg Tablets help prevent blood glucose levels from rising excessively after meals.\u003c\/span\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eUses\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eTreatment of Type 2 Diabetes Mellitus\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow it works\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets combine the actions of Sitagliptin and Metformin. Metformin works by reducing hepatic glucose production, lowering intestinal glucose absorption, and improving peripheral glucose uptake and utilization. Sitagliptin enhances the body's incretin system, increasing insulin release and decreasing glucagon levels in a glucose-dependent manner. This combination helps maintain blood glucose levels within the normal range, especially after meals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIstamet 50 mg\/1000 mg Tablet helps the pancreas produce more insulin, improves insulin sensitivity, and decreases excess glucose production by the liver. It helps control postprandial (after-meal) blood sugar spikes and does not cause weight gain even with long-term use. Istamet 50 mg\/1000 mg Tablet plays a vital role in controlling blood sugar levels and helps prevent serious diabetes-related complications, such as:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eVision loss (retinopathy)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eKidney damage (nephropathy)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eNerve damage (neuropathy)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDiabetic foot ulcers\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDelayed wound healing\u003c\/span\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow to use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eTake Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets exactly as prescribed by your doctor. Swallow the tablet whole with water; do not crush, break, or chew it.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eSide Effects\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eHypoglycemia (low blood sugar)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eRunny nose\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eSore throat\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eUpper respiratory tract infection\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eDiarrhea\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eNausea\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eVomiting\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eFlatulence (gas)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eStomach upset\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eIndigestion\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eGeneral weakness\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eHeadache\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eSafety Advice\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eAvoid consumption of alcohol while on treatment with Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets, as it may increase the risk of lactic acidosis and hypoglycemia.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eSitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets are only recommended during pregnancy if the potential benefits outweigh the risks. Consult your doctor before starting this medication if you are pregnant or planning to conceive.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eStorage Conditions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli dir=\"ltr\" aria-level=\"1\"\u003e\n\u003cp dir=\"ltr\" role=\"presentation\"\u003e\u003cspan\u003eStore at a temperature below 86°F (30 °C).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eFAQs\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhat is the use of Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablet?\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThey are used to treat Type 2 Diabetes Mellitus by helping control blood sugar levels\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eHow does Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets work?\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMetformin reduces glucose production in the liver, lowers glucose absorption in the gut, and improves insulin sensitivity. Sitagliptin increases incretin hormones, which stimulate insulin release and reduce glucagon secretion, helping regulate blood sugar levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhat are the signs of diabetes?\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIncreased hunger, excessive thirst, frequent urination (especially at night), unexplained weight loss, fatigue, blurred vision, slow healing of wounds or sores, and frequent infections.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eAre Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets used for the treatment of type 1 diabetes?\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNo. Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets are only prescribed for the treatment of type 2 diabetes, also called non-insulin-dependent diabetes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eWhy do Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets need to be taken with food?\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets need to be taken with food to avoid stomach upset. Take it as prescribed by your doctor.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cstrong\u003eCan I take crushed Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets?\u003c\/strong\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eDo not crush or chew Sitagliptin Phosphate 50mg \u0026amp; Metformin Hydrochloride 1000mg Tablets, as it may release all of the medicine at once and cause side effects. Take it whole with food, or as directed by your doctor.\u003c\/span\u003e\u003c\/p\u003e","brand":"Generic Remedy","offers":[{"title":"Sitagliptin 50mg \u0026 Metformin Hydrochloride 1000mg Tablets IP","offer_id":43249441177709,"sku":"GR351","price":65.63,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0619\/7349\/5917\/files\/sitagliptin_50mg_metformin_1000mg_tablets.png?v=1772514836","url":"https:\/\/www.genericremedy.com\/products\/sitagliptin-phosphate-50mg-metformin-hydrochloride-1000mg","provider":"Generic Remedy","version":"1.0","type":"link"}