Product Description

Apixaban 5 mg Tablets IP is an oral anticoagulant (blood thinner) used for the prevention and treatment of thromboembolic disorders. It helps reduce the risk of blood clot formation, which can lead to serious conditions such as stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE).

Apixaban belongs to a class of medicines known as direct oral anticoagulants (DOACs). The 5 mg strength is commonly prescribed in adults with atrial fibrillation not caused by heart valve disease, and for the treatment and prevention of venous thromboembolism.

Uses

• Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation
  

• Treatment of deep vein thrombosis (DVT)
  

• Treatment of pulmonary embolism (PE)
  

• Prevention of recurrent DVT and PE
  

• Long-term anticoagulation in patients at risk of clot formation, as advised by a physician
  
  

How it Works

Apixaban 5 mg Tablets IP works by selectively inhibiting Factor Xa, a key enzyme involved in the blood clotting process.

• Inhibits Factor Xa, reducing thrombin generation
  

• Prevents conversion of fibrinogen to fibrin
  

• Stops existing clots from enlarging and reduces the formation of new clots
  

This targeted action provides effective anticoagulation without directly affecting platelets.

Benefits

• Reduces the risk of stroke and systemic embolism
  

• Effective treatment of DVT and PE
  

• Lower risk of major bleeding compared to conventional anticoagulants
  

• Predictable anticoagulant effect with fixed dosing
  

• No routine INR or coagulation monitoring required
  

• Suitable for long-term use under medical supervision
  

How to Use

Take Apixaban 5 mg Tablets IP exactly as prescribed by your doctor.

• Usually taken twice daily
  

• Can be taken with or without food
  

• Swallow the tablet whole with water
  

If swallowing is difficult, the tablet may be crushed and mixed with water, apple juice, or applesauce and taken immediately, as directed by your doctor.

Do not discontinue the medicine without consulting your healthcare provider.

Side Effects

Common side effects may include:

• Easy bruising
  

• Nosebleeds
  

• Bleeding gums
  

• Nausea
  

• Mild rash
  

• Increased menstrual bleeding
  

Serious side effects (seek immediate medical attention):

• Blood in urine (red, pink, or brown urine)
  

• Black or tarry stools
  

• Coughing up blood or vomiting blood
  

• Severe headache, dizziness, or weakness
  

• Uncontrolled or prolonged bleeding
  

Safety Advice

• Apixaban increases bleeding risk; avoid activities that may cause injury
  

• Inform your doctor if you have liver disease, kidney disease, bleeding disorders, or recent surgery
  

• Avoid taking other blood thinners unless prescribed
  

• Inform your doctor before any surgery, dental, or invasive procedure
  

• Excessive alcohol consumption may increase bleeding risk
  

• Do not stop the medicine abruptly, as this may increase the risk of stroke or blood clots
  

Storage Conditions

• Store below 30°C (86°F)
  

• Protect from light and moisture
  

• Keep out of reach of children
  

FAQs

What is Apixaban 5 mg Tablets IP used for?

It is used to prevent and treat blood clots, including stroke prevention in atrial fibrillation and treatment of DVT and PE.

Does Apixaban 5 mg require blood monitoring?

No, routine INR or coagulation monitoring is not required.

What should I do if I miss a dose?

Take the missed dose as soon as you remember on the same day. Do not take two doses together.

Can I stop Apixaban 5 mg Tablets IP on my own?

No. Stopping apixaban suddenly may increase the risk of stroke or clot formation. Always consult your doctor.

Is Apixaban 5 mg safe during pregnancy or breastfeeding?

Apixaban is not recommended during pregnancy or breastfeeding unless clearly advised by a doctor.

Which painkillers are safe with Apixaban?

Avoid NSAIDs such as ibuprofen unless prescribed. Paracetamol is generally preferred.