Product Description

Dapagliflozin 10mg, Glimepiride 1mg & Metformin 500 mg ER Tablet is an antidiabetic medicine used to treat type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic condition affecting glucose metabolism, caused by insulin resistance or insufficient insulin production. This combination helps control blood sugar when single or dual therapies are inadequate.

Uses

Treatment of Type 2 Diabetes Mellitus.

How it works

This tablet contains three antidiabetic medicines: Dapagliflozin (an SGLT2 inhibitor), Metformin (a biguanide), and Glimepiride (a sulfonylurea).

• Dapagliflozin promotes the excretion of excess glucose through urine.

• Metformin reduces glucose production in the liver and slows intestinal glucose absorption.

• Glimepiride stimulates insulin secretion from the pancreas.

• Together, they provide comprehensive glycemic control.

Benefits

• Effectively treats type 2 diabetes mellitus by lowering blood sugar levels through multiple mechanisms.

• Dapagliflozin helps remove excess sugar via urine, Metformin reduces glucose production and absorption, and Glimepiride boosts insulin secretion.

• Used alongside diet and exercise to improve blood sugar control and reduce cardiovascular risks.

How to use

• Take as advised by your doctor; do not exceed the prescribed dose.

• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.

• Take with meals to minimize gastrointestinal side effects.

Side Effects

Common side effects may include:

• Headache

• Nausea

• Stomach upset

• Vomiting

• Abdominal pain

• Allergic reactions

• Hypoglycemia (low blood sugar)

Serious side effects (seek immediate medical help):

• Genital or urinary tract infections (more common with Dapagliflozin)

• Volume depletion or hypotension (with Dapagliflozin)

• Lactic acidosis (with Metformin; symptoms: muscle pain, difficulty breathing, abdominal pain)

• Euglycemic diabetic ketoacidosis (DKA; symptoms: nausea, abdominal pain, fruity breath)

• Severe hypoglycemia (with Glimepiride)

Report any persistent or severe symptoms to your doctor.

Safety Advice

• Alcohol: Avoid excessive consumption, as it increases the risk of lactic acidosis and other side effects.

• Pregnancy and Breastfeeding: Limited studies; inform your doctor if pregnant or planning pregnancy. Use only if the benefits outweigh the risks. Not recommended while breastfeeding.

• Contraindications: Do not use if you have type 1 diabetes, diabetic ketoacidosis, severe renal/hepatic impairment, or hypersensitivity to the ingredients.

• Drug Interactions: Inform your doctor about medications like insulin, NSAIDs, diuretics, or CYP inducers/inhibitors, as they may affect efficacy or increase risks.

• Monitoring: Regular blood glucose, renal function, and ketone monitoring are recommended. Watch for signs of infection or dehydration.

• Consult your doctor if you have heart disease or are elderly.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of Dapagliflozin 10mg, Glimepiride 1mg & Metformin 500mg Tablet?

Dapagliflozin 10mg, Glimepiride 1mg & Metformin 500mg Tablet is used for the treatment of Type II Diabetes.

How does Dapagliflozin 10mg, Glimepiride 1mg & Metformin 500mg Tablet work?

Dapagliflozin 10mg, Glimepiride 1mg & Metformin 500mg Tablet contains Dapagliflozin, Metformin, and Glimepiride, which work by increasing the amounts of certain natural substances that lower blood sugar when it is high.

If I am taking regular Insulin, do I need to talk to a Doctor?

Please consult your doctor if you have concerns and for more information on this.

What to do if I forget to take my regular prescribed dose?

If you forget to take Dapagliflozin 10mg, Glimepiride 1mg & Metformin 500mg Tablet, take it as soon as you remember. However, if it is time for the next dose, avoid taking it and do not double-dose to make up for the missed dose. Taking an overdose might cause your sugar level to fall rapidly.