Product Description

Dapagliflozin 10 mg & Vildagliptin 100 mg SR Tablet is an antidiabetic medication used for the management of Type 2 Diabetes Mellitus, a chronic metabolic disorder characterized by insulin resistance and/or impaired insulin secretion leading to elevated blood glucose levels.

This combination contains:

• Dapagliflozin, a Sodium-Glucose Cotransporter-2 (SGLT2) inhibitor, lowers blood glucose by promoting renal excretion of glucose through urine.

• Vildagliptin, a Dipeptidyl Peptidase-4 (DPP-4) inhibitor in a sustained-release (SR) formulation, enhances incretin hormone activity, thereby increasing insulin secretion and decreasing glucagon release in a glucose-dependent manner. 

Uses

• Treatment and management of Type 2 Diabetes Mellitus to improve glycemic control.

How it works

• Dapagliflozin inhibits SGLT2 in the proximal renal tubules, reducing glucose reabsorption and increasing urinary glucose excretion, which lowers blood glucose levels.

• Vildagliptin SR inhibits the DPP-4 enzyme, increasing levels of incretin hormones (GLP-1 and GIP), which stimulate insulin secretion and suppress glucagon release, particularly after meals, thereby reducing both fasting and postprandial blood glucose. 

Benefits

• Provides complementary mechanisms of action for improved glycemic control.

• Dapagliflozin helps reduce blood glucose by increasing glucose elimination via urine.

• Vildagliptin SR improves insulin response and reduces glucagon secretion, helping to control blood sugar throughout the day with once-daily dosing.

How to use

• Take the tablet exactly as prescribed by your healthcare provider.

• Swallow the tablet whole with water; do not crush, chew, or break the tablet to maintain the sustained-release properties.

• Do not exceed the recommended dose.

Side Effects

• Headache

• Nausea

• Stomach upset

• Vomiting

• Abdominal pain

• Allergic reactions

• Increased risk of urinary tract and genital infections (due to Dapagliflozin)

• Hypoglycemia (especially if used with insulin or sulfonylureas)

• Dizziness

• Frequent urination

Safety Advice

• Avoid alcohol consumption during treatment as it may increase side effects.

• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

• Use caution in patients with renal impairment; Dapagliflozin is contraindicated in severe renal dysfunction.

• Be aware of the rare risk of diabetic ketoacidosis with SGLT2 inhibitors.

• Monitor blood glucose regularly as advised by your healthcare provider. 

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of Dapagliflozin 10 mg & Vildagliptin 100 mg SR Tablet?

Dapagliflozin 10 mg & Vildagliptin 100 mg SR Tablet is an antidiabetic medicine used to treat Type II Diabetes. Dapagliflozin helps to lower blood sugar by causing the kidneys to remove excess sugar from the body through urine. Vildagliptin stimulates insulin release in response to glucose, thereby lowering both fasting and post-meal blood sugar levels.

What should I do if I miss my regular prescribed dose?

If you forget to take Dapagliflozin 10 mg & Vildagliptin 100 mg SR Tablet, take it as soon as you remember. However, if it's time for the next dose, skip the missed dose. Do not double-dose to make up for the missed dose, as it may cause your sugar level to fall rapidly.

How does Dapagliflozin 10 mg & Vildagliptin 100 mg SR Tablet work?

In this combination, Dapagliflozin lowers blood sugar by helping the kidneys eliminate excess glucose through urine, while Vildagliptin boosts insulin secretion in response to glucose, reducing both fasting and post-meal blood sugar levels.

What are the side effects of Dapagliflozin 10 mg & Vildagliptin 100 mg SR Tablet?

It may cause headache, nausea, stomach upset, vomiting, abdominal pain, allergic reactions, painful urination, hypoglycaemia (low blood sugar), dizziness, and frequent urination.

Is Dapagliflozin 10 mg & Vildagliptin 100 mg SR Tablet safe to use?

It is generally safe for most patients when used as per the dose and duration advised by a doctor.