Product Description

Diclofenac Sodium Prolonged Release Tablets IP 100 mg is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of pain and inflammation associated with musculoskeletal and joint disorders. It is commonly prescribed for conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other inflammatory conditions.

Diclofenac works by reducing pain, swelling, and stiffness through inhibition of cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins—chemical mediators involved in pain and inflammation. The prolonged-release formulation ensures sustained drug release over an extended period, providing long-lasting pain relief with once-daily dosing.

This medicine is intended for use under medical supervision and should not be used for prolonged periods without consulting a doctor due to potential gastrointestinal, cardiovascular, and renal risks.

Uses

Diclofenac Sodium Prolonged Release Tablets IP 100 mg are indicated for the treatment of:

• Osteoarthritis
  

• Rheumatoid arthritis
  

• Ankylosing spondylitis
  

• Chronic musculoskeletal pain
  

• Inflammatory joint disorders
  

• Post-traumatic or postoperative pain (as prescribed)
  
  

How it Works

Diclofenac Sodium Prolonged Release Tablets IP 100 mg act by inhibiting both COX-1 and COX-2 enzymes. This inhibition reduces the synthesis of prostaglandins at sites of inflammation and tissue injury, leading to decreased pain, swelling, and stiffness.

The prolonged-release formulation allows gradual release of diclofenac throughout the day, maintaining therapeutic levels for extended pain control while reducing dosing frequency.

Benefits

• Provides sustained relief from pain and inflammation
  

• Improves joint mobility and reduces stiffness
  

• Suitable for chronic inflammatory conditions requiring once-daily dosing
  

• Prolonged-release formulation enhances patient compliance
  

• Effective in managing moderate to severe inflammatory pain
  

How to Use

Take Diclofenac Sodium Prolonged Release Tablets IP 100 mg exactly as prescribed by your doctor.

• Take the tablet once daily, preferably after meals
  

• Swallow the tablet whole with a full glass of water
  

• Do not crush, chew, or break the tablet, as this may alter the prolonged-release effect
  

• If a dose is missed, take it as soon as you remember, unless it is close to the next dose
  

• Do not take a double dose to make up for a missed one
  
  

Side Effects

Common side effects may include:

• Nausea
  

• Vomiting
  

• Stomach pain or discomfort
  

• Indigestion
  

• Dizziness or headache
  

Less common but serious side effects:

• Stomach ulcers or gastrointestinal bleeding
  

• Increased blood pressure
  

• Kidney function impairment
  

• Cardiovascular events (with long-term use)
  

• Allergic reactions such as rash or swelling
  

Consult your doctor immediately if you experience severe stomach pain, black stools, chest pain, or signs of an allergic reaction.

Safety Advice

• Alcohol: Avoid excessive alcohol consumption, as it increases the risk of stomach irritation and bleeding
  

• Pregnancy: Not recommended, especially during the third trimester, due to the risk of fetal complications
  

• Breastfeeding: Use with caution; consult your doctor before use
  

• Medical Conditions: Inform your doctor if you have a history of stomach ulcers, heart disease, kidney or liver problems
  

• Driving: May cause dizziness; avoid driving or operating machinery if affected
  

• Long-term Use: Prolonged use should be avoided unless advised by a doctor due to potential GI, renal, and cardiovascular risks
  

Storage Conditions

• Store below 30°C (86°F)
  

• Keep in a cool, dry place away from sunlight and moisture
  

• Keep out of reach of children
  

FAQs

What is Diclofenac Sodium Prolonged Release Tablets IP 100 mg used for?

It is used to relieve pain and inflammation in conditions such as arthritis, joint disorders, and musculoskeletal pain.

Can Diclofenac Sodium Prolonged Release Tablets IP 100 mg be taken long-term?

Long-term use is not recommended unless prescribed by a doctor, as it may increase the risk of stomach, kidney, or heart problems.

Can I stop taking the medicine if I feel better?

Yes, as it is often prescribed for symptom relief. However, consult your doctor before stopping the medication.

Is this medicine addictive?

No, Diclofenac Sodium Prolonged Release Tablets IP 100 mg is not addictive.

Can this medicine cause stomach problems?

Yes, NSAIDs can cause stomach irritation or ulcers, especially with prolonged use. Taking the tablet after food may help reduce stomach discomfort.

Is it safe during pregnancy?

No, it should be avoided during pregnancy, particularly in the third trimester.

What should I do if I miss a dose?

Take the missed dose when remembered, unless it is nearly time for the next dose. Do not double the dose.