Product Description

Itopride 50 mg Tablet is used in the treatment of disorders associated with reduced gastrointestinal motility.

It also helps manage gastrointestinal disorders such as dyspepsia (indigestion), bloating (feeling of stomach tightness due to gas), upper abdominal pain, anorexia (eating disorder), heartburn, nausea, and vomiting.

In normal digestion, food moves through the digestive tract (oesophagus, stomach, small intestine, and large intestine) via rhythmic contractions known as peristalsis, which is referred to as gastric motility. When gastric motility is impaired, these contractions do not function properly, leading to various gastrointestinal issues.

Uses

• Treatment of Heartburn, Nausea, Vomiting, and Bloating.

• It is also effective for non-ulcer dyspepsia and other symptoms of reduced gastrointestinal motility.

How it works

Itopride 50 mg Tablet works by inhibiting acetylcholinesterase, which increases acetylcholine levels in the body. This enhances gastrointestinal peristalsis, accelerates gastric emptying, and facilitates the movement of food through the digestive tract. Additionally, it blocks D2 receptors in the chemoreceptor trigger zone (CTZ) of the brain, helping to prevent nausea and vomiting.

Benefits

Itopride 50 mg Tablet is a gastroprokinetic agent that improves the movement of food from the mouth through the stomach and intestines. It is used to treat symptoms such as heartburn, vomiting, nausea, bloating (stomach swelling due to gas buildup), non-ulcer dyspepsia (indigestion), and stomach discomfort or pain. Enhancing gastric motility, it reduces heartburn and acts on the brain's chemoreceptor trigger zone to prevent vomiting.

How to use

Take Itopride 50 mg Tablet on an empty stomach, preferably 1 hour before a meal, or as directed by your doctor. Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.

Side Effects

Common side effects include:

• Diarrhoea

• Stomach pain

• Headache

• Dry mouth

• Drowsiness

If any side effects persist or worsen, or if you experience rare but serious symptoms such as allergic reactions (e.g., rash, itching), extrapyramidal effects (e.g., tremors), or irregular heartbeat, consult your doctor immediately.

Safety Advice

• Alcohol: The interaction of alcohol with Itopride 50 mg Tablet is not fully known. It is advisable to consult a doctor before consuming alcohol while taking this medication, as it may exacerbate side effects like drowsiness.

• Pregnancy: The safety of Itopride 50 mg Tablet in pregnant women is not well-established. It should only be used if the potential benefits outweigh the risks, as determined by your doctor.

• Breastfeeding: Itopride may pass into breast milk and could affect the infant. It is generally not recommended for breastfeeding mothers unless advised by a doctor.

• Other Precautions: Avoid driving or operating machinery if you experience drowsiness. Inform your doctor about any existing medical conditions or medications you are taking.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of Itopride 50 mg Tablet?

Itopride 50 mg Tablet is used in the treatment of disorders associated with reduced gastrointestinal motility. Besides this, Itopride 50 mg Tablet also treats gastrointestinal disorders like dyspepsia (indigestion), bloating (feeling of stomach tightness due to gas), upper abdominal pain, anorexia (eating disorder), heartburn, nausea and vomiting.

How does Itopride 50 mg Tablet work?

Itopride 50 mg Tablet works by increasing the level of acetylcholine concentration, which in turn increases the gastrointestinal peristalsis movement, thereby accelerating gastric emptying time and easing the movement of food through the entire gastrointestinal tract. Itopride 50 mg Tablet also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.

Does Itopride 50 mg Tablet cause diarrhoea?

Yes, Itopride 50 mg Tablet may cause diarrhoea as a common side effect. However, if the condition persists, worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Itopride 50 mg Tablet to prevent dehydration.

Does Itopride 50 mg Tablet cause gynecomastia?

Yes, Itopride 50 mg Tablet may cause gynecomastia (enlargement of breast tissue in males) in some people. It is not necessary for everyone taking Itopride 50 mg Tablet to experience this side effect. However, if you notice any signs of breast swelling, please consult a doctor immediately.

Can I take Itopride 50 mg Tablet with dicyclomine?

No, you are not recommended to take Itopride 50 mg Tablet with dicyclomine, as co-administration of these two medicines may reduce the effect of Itopride 50 mg Tablet. However, please consult your doctor before taking Itopride 50 mg Tablet with other medicines.

Is Itopride 50 mg Tablet safe for patients with gastrointestinal haemorrhage?

No, Itopride 50 mg Tablet is not recommended for patients with gastrointestinal haemorrhage (internal bleeding of intestine and stomach) as it may lead to gastrointestinal perforation (ruptured bowel).