Product Description

Levetiracetam Tablets IP 750 mg is an antiepileptic drug (AED) used to control certain types of seizures in epilepsy, including partial-onset (focal) seizures (with or without secondary generalization), myoclonic seizures, and primary generalized tonic-clonic seizures.

It is suitable for adults and children ≥4 years as monotherapy or adjunctive therapy. Epilepsy is a chronic neurological disorder characterized by recurrent, unprovoked seizures due to abnormal electrical activity in the brain, which may affect one side (focal) or both sides (generalized).

Levetiracetam does not cure epilepsy but helps prevent seizures while used; abrupt discontinuation may increase seizure risk. It has a favorable pharmacokinetic profile with minimal drug interactions.

Uses

Levetiracetam 750 mg Tablets IP are indicated for:

• Adjunctive therapy for partial-onset seizures (focal aware, focal impaired awareness, or evolving to bilateral tonic-clonic) in adults and children ≥4 years (≥20 kg body weight)

• Adjunctive or monotherapy for myoclonic seizures in juvenile myoclonic epilepsy (patients ≥12 years)

• Adjunctive therapy for primary generalized tonic-clonic seizures in idiopathic generalized epilepsy (patients ≥6 years)

Not for absence seizures, status epilepticus, or non-epileptic conditions. Dose titration is essential to minimize side effects.

How it works

Levetiracetam 750 mg Tablets contain levetiracetam, a unique AED that binds to synaptic vesicle protein 2A (SV2A) on neuronal presynaptic membranes, modulating neurotransmitter release and inhibiting hypersynchronization of epileptiform burst firing.

Unlike traditional AEDs, it does not directly affect voltage-gated sodium channels, GABA, or glutamate receptors. This action suppresses abnormal electrical signals in the brain, prevents their spread to adjacent areas, and reduces seizure frequency and severity without causing significant sedation or cognitive impairment in most patients. 

It is effective across focal and generalized epilepsy types but does not alter the underlying disease progression.

Benefits

Levetiracetam 750 mg tablets effectively reduce seizure frequency (by 50% or more in ~40–60% of patients per clinical trials) when used alone or with other AEDs, improving daily functioning and quality of life in epilepsy.

It offers rapid onset (within 1–2 weeks), once- or twice-daily dosing for convenience, and a low risk of pharmacokinetic interactions, making it suitable for polytherapy.

 By stabilizing neuronal activity, it minimizes disruptions from seizures, such as injury or status epilepticide, and supports long-term seizure control without tolerance development.

How to use

Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break, or chew it. Levetiracetam syrup dose: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Side Effects

Most side effects are mild and may improve with time or dose adjustment. Common side effects (affecting 10–20% of patients) include:

• Daytime drowsiness or somnolence

• Dizziness or light-headedness

• Disturbed sleep or insomnia

• Sleepiness or fatigue

• General weakness or asthenia

Safety Advice

• Alcohol: Avoid alcohol, as it exacerbates CNS depression, increasing risks of drowsiness, dizziness, impaired coordination, and potentially life-threatening respiratory depression or coma.

• Pregnancy: Category C (animal studies show no teratogenicity; human data from registries indicate low malformation risk ~2–3%, similar to the general population, but dose adjustments are needed due to increased clearance). Use only if benefits outweigh risks (e.g., uncontrolled seizures pose greater fetal harm); folic acid supplementation (0.4–1 mg/day) recommended. Enroll in pregnancy registries; effective contraception is advised if applicable.

• Breastfeeding: Levetiracetam passes into breast milk (~10% of maternal dose); monitor infants for drowsiness or poor feeding. Generally compatible, but weigh benefits—consult a doctor for alternatives if concerned.

• Driving/Operating Machinery: May cause drowsiness, dizziness, or coordination issues; do not drive or operate machinery until effects are known (seizure-free for 6–12 months typically required).

Storage Conditions

• Store at a temperature below 30°C (86°F), in a cool, dry place away from direct sunlight, heat, and excessive moisture.

FAQs

What are the levetiracetam tablets used for?

Levetiracetam is used to treat seizures (fits) due to epilepsy.

How does Levetiracetam Tablets IP 750 mg work?

Levetiracetam dosage works by slowing down the abnormal signals in the brain, which cause episodes of seizures.

What would happen if I suddenly stopped using levetiracetam?

Do not stop taking Levetiracetam Tablets IP 750 mg until instructed by your doctor. You may get side effects like confusion, depression, nervousness, sweating, and diarrhea. Your doctor may lower the levetiracetam dose if using it for more than 2-4 weeks of treatment to reduce side effects.

What will happen after using levetiracetam tablets for a long time?

Levetiracetam Tablets IP 750 mg are prescribed for long-term use in the treatment of epilepsy. So, if Levetiracetam Tablets IP 750 mg Tablet is prescribed for more than 4 weeks, your doctor may reduce the dose before stopping it completely to prevent withdrawal symptoms.

Can levetiracetam lead to unexpected puberty or retarded growth?

Yes, if you feel unexpected puberty or slowing in growth, please consult your doctor and do as your doctor advises.

Can I stop taking the levetiracetam dosage if I feel better?

No, even if you feel better, you should not stop the medication without consulting your doctor, as this might increase the episodes of seizures.

Are there any foods and beverages that I need to avoid while taking the levetiracetam dose?

Caffeine is a stimulant that may reduce the calming effects of levetiracetam use. So, it is advisable to avoid caffeine intakes like coffee, tea, cola, or chocolate containing caffeine.

I have gained weight since I started using levetiracetam. Is it because of the Levetiracetam Tablets IP 750 mg Tablet? What should I do?

Yes, Levetiracetam Tablets may cause weight gain as an uncommon side effect. Follow a healthy diet and exercise regularly to maintain a proper weight. Talk to the doctor if you have any concerns.

How long does it take for the levetiracetam side effects to appear?

Levetiracetam side effects might take a few weeks to begin working. You may still have seizures during this time.

For how long do I need to take Levetiracetam Tablets?

Levetiracetam Tablets IP 750 mg should be taken for as long as it has been prescribed by the doctor. The duration of treatment depends on your condition and response to the treatment.

Will I get addicted to Levetiracetam Tablets if I use them for a long time?

Levetiracetam use does not cause addiction as it is not a habit-forming medicine.

What symptoms may occur from excessive levetiracetam or overdose?

An overdose of Levetiracetam Tablets IP 750 mg may cause sleepiness, aggression, agitation, decreased alertness, breathing problems, and coma. Consult the doctor if you have exceeded the recommended dose of Levetiracetam Tablets IP 750 mg Tablet.