Product Description

Linagliptin Tablet 5mg IP is an antidiabetic medicine used to control high blood sugar levels in people with type 2 diabetes mellitus. It helps prevent serious complications of diabetes, such as kidney damage, blindness, and may reduce the risk of heart attack or stroke. Linagliptin can be prescribed alone or with other diabetes medications. Diabetes management is most effective with a balanced diet and regular exercise. The dose depends on your condition, blood sugar levels, and other medicines. Taking it with meals may lower the risk of stomach discomfort.

Uses

Management of Type 2 diabetes mellitus.

How it works

Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that regulates levels of incretin hormones in the body. This helps lower blood sugar levels, especially after meals, while reducing the risk of hypoglycemia (low blood sugar) since its action depends on glucose presence.

Benefits

In Treatment of Type 2 diabetes mellitus: Linagliptin helps lower blood glucose levels, reducing the risk of complications like kidney damage, eye problems, nerve issues, and limb loss. It also lowers the risk of heart disease and stroke. Regular use with diet and exercise promotes a normal, healthy life and protects future health.

How to use

• Take the dose and duration as advised by your doctor.

• Swallow the tablet whole; do not chew, crush, or break it.

• Take with food to minimize stomach discomfort.

Side Effects

Common side effects may include:

• Nausea

• Headache

• Hypoglycemia (low blood glucose level)

• Tremors

• Dizziness

Serious side effects (seek immediate medical help):

• Pancreatitis (severe abdominal pain, nausea, vomiting)

• Severe joint pain or hypersensitivity reactions

• Bullous pemphigoid (blistering skin rash)

• Allergic reactions (e.g., swelling, difficulty breathing)

Report any persistent or severe symptoms to your doctor.

Safety Advice

• Alcohol: Unsafe to consume with Linagliptin, as it may increase hypoglycemia risk.

• Pregnancy: In rare cases, a doctor may prescribe it for life-threatening conditions if the benefits outweigh the risks. Consult your doctor.

• Breastfeeding: Unsafe to use during breastfeeding, as it may cause toxicity to the baby.

• Contraindications: Do not use if you have type 1 diabetes, diabetic ketoacidosis, or hypersensitivity to Linagliptin.

• Drug Interactions: Inform your doctor about medications like insulin, sulfonylureas, or CYP3A4/2C9 inducers/inhibitors, as they may affect blood sugar control.

• Monitoring: Regular blood glucose monitoring is advised. Watch for signs of pancreatitis or allergic reactions.

• Consult your doctor if you have kidney/liver issues, heart disease, or are elderly.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

Can the use of Linagliptin 5mg IP cause lactic acidosis?

Yes, the use of Linagliptin 5mg IP can lead to lactic acidosis, which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin, and therefore it is avoided in patients with underlying kidney disease, old age patients, or those who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, a feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain, or slow heart rate. If you have these symptoms, stop taking Linagliptin 5mg IP and immediately consult your doctor.

What are the possible side effects of Linagliptin 5mg IP?

The use of Linagliptin 5mg IP may cause some common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhoea, and headache. It can also lead to a serious but rare side effect known as lactic acidosisProlonged use may also result in vitamin B12 deficiency.

Are there any specific conditions in which Linagliptin 5mg IP should not be taken?

The use of Linagliptin 5mg IP should be avoided in patients with known allergy to any of the components of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis. Therefore, consult your doctor before using Linagliptin 5mg IP.

Is it safe to take alcohol while I am also taking Linagliptin 5mg IP?

No, it is not safe to take Linagliptin 5mg IP along with alcohol. Doing so can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition, or kidney dysfunction. However, if you are not sure, consult your doctor.