Product Description

Linagliptin 5 mg & Dapagliflozin 10 mg IP is used to treat type 2 diabetes mellitus. Type 2 diabetes mellitus (also known as non-insulin-dependent diabetes) is a condition where blood glucose levels are elevated due to insulin deficiency, insulin resistance, or both. This combination helps control blood sugar levels and may reduce cardiovascular risks.

Uses

Treatment of Type 2 diabetes mellitus

How it works

This tablet contains two antidiabetic medicines: Dapagliflozin (an SGLT2 inhibitor) and Linagliptin (a DPP-4 inhibitor).

• Dapagliflozin promotes the excretion of excess glucose through urine, reducing blood sugar levels.

• Linagliptin increases incretin hormone levels, enhancing insulin secretion from the pancreas and reducing glucagon release.

• Together, they provide comprehensive glycemic control.

Benefits

• Effectively manages type 2 diabetes mellitus by lowering blood glucose levels.

• Dapagliflozin helps remove excess sugar via urine, while Linagliptin decreases hormones that raise blood glucose and increases insulin release.

• Used in combination with diet and exercise to improve blood sugar control and reduce cardiovascular risks.

How to use

• Take with or without food.

• Swallow the tablet whole with a glass of water; do not break, chew, or crush it.

• Take as prescribed by your doctor, usually once daily. Do not skip doses.

Side Effects

Common side effects may include:

• Stomach upset

• Hypoglycaemia (low blood sugar levels)

• Nausea

• Vomiting

• Diarrhoea

• Headache

• Constipation

• Dizziness

• Dry mouth

• Fatigue

• Urinary tract infections

Serious side effects (seek immediate medical help):

• Genital infections

• Volume depletion or hypotension (with Dapagliflozin)

• Pancreatitis (with Linagliptin; symptoms: severe abdominal pain)

• Euglycemic diabetic ketoacidosis (DKA; symptoms: nausea, abdominal pain, fruity breath)

• Allergic reactions (e.g., rash, swelling)

Report any unusual symptoms to your doctor promptly.

Safety Advice

• Alcohol: Avoid consumption, as it may cause serious side effects like increased hypoglycemia.

• Pregnancy and Breastfeeding: Inform your doctor if pregnant or planning pregnancy. May be prescribed if benefits outweigh risks; use with caution while breastfeeding.

• Kidney Conditions: Inform your doctor if you have kidney disease; dose adjustments or alternatives may be needed.

• Contraindications: Do not use if you have severe renal impairment, hepatic disease, a history of pancreatitis, diabetic ketoacidosis, or hypersensitivity to the ingredients. Not for type 1 diabetes.

• Drug Interactions: Inform your doctor about medications like diuretics (increase DKA risk), insulin, corticosteroids, or CYP inducers/inhibitors, as they may affect efficacy or side effects.

• Monitoring: Regular blood glucose, kidney function, and ketone monitoring are recommended. Watch for signs of infection or dehydration.

• Consult your doctor if you have heart disease or are elderly.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of Linagliptin and Dapagliflozin?

Linagliptin 5 mg & Dapagliflozin 10 mg IP belong to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus.

How does Linagliptin 5 mg & Dapagliflozin 10 mg IP work?

Linagliptin 5 mg & Dapagliflozin 10 mg IP is a combination medicine containing Linagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce sugar production by cells in the liver and delays sugar absorption from the intestines.

Does Linagliptin 5 mg & Dapagliflozin 10 mg IP cause hypoglycaemia?

Hypoglycemia/low blood sugar levels could be the side effect of Linagliptin 5 mg & Dapagliflozin 10 mg IP. Hypoglycemia generally occurs when Linagliptin 5 mg & Dapagliflozin 10 mg IP is taken along with other antidiabetic medicines, without food or with alcohol. Consume sugary food such as candy or fruit juice if you experience hypoglycemic symptoms such as dizziness, cold sweats, anxiety, or tremors. Regularly monitor blood glucose levels while taking Linagliptin 5 mg & Dapagliflozin 10 mg IP.

What are the causes of diabetes?

Low-fibre diets, high-fat diets, sugary diets, obesity, smoking, stress, lack of exercise, age, genetic factors, and certain medical conditions are the common causes of diabetes.