Product Description

Losartan 50mg & Amlodipine 5mg Tablets IP are used to treat high blood pressure (hypertension). Hypertension is a condition where blood pressure remains consistently high in the arteries, increasing the risk of cardiovascular diseases such as a heart attack or stroke.

Uses

Treatment of High blood pressure (hypertension).

How it works

This tablet is a combination of two medicines: Losartan (an angiotensin II receptor antagonist) and Amlodipine (a calcium channel blocker).

• Losartan blocks angiotensin II receptors, preventing blood vessel constriction and promoting vasodilation to reduce blood pressure.

• Amlodipine inhibits calcium entry into vascular smooth muscle cells, widening blood vessels for improved blood flow.

• Together, they effectively lower blood pressure by relaxing and dilating blood vessels.

Benefits

• Treats high blood pressure (hypertension) to reduce the risk of cardiovascular events.

• Amlodipine may also help relieve symptoms of angina (chest pain) in patients with coronary artery disease, as part of overall management.

How to use

• Take the tablet whole with water; avoid crushing, breaking, or chewing it.

• Take it at the same time each day, with or without food, as prescribed by your doctor.

• Your doctor may adjust the dose based on your response. Do not stop without consulting your doctor.

Side Effects

Common side effects may include:

• Sleepiness

• Taste changes

• Ankle swelling

• Headache

• Flushing

• Dizziness

• Tiredness

• Palpitations

• Upset stomach

• Hyperkalaemia (high potassium levels)

Safety Advice

• Alcohol: Avoid alcohol, as it may increase the risk of low blood pressure and side effects like dizziness, fainting, light-headedness, or headache.

• Pregnancy and Breastfeeding: Consult your doctor before use if planning to conceive or are currently pregnant. Losartan may harm the fetus; Amlodipine's effects are less clear. Use only if the benefits outweigh the risks.

• Kidney/Liver Conditions: Losartan may affect kidney function; seek advice if you have kidney problems. Use caution in liver disease, as Amlodipine is metabolized by the liver.

• Contraindications: Do not use if you have severe aortic stenosis, bilateral renal artery stenosis, or hypersensitivity to ARBs or CCBs. Not recommended during pregnancy or in severe hypotension.

• Drug Interactions: Inform your doctor about medications like potassium supplements (risk of hyperkalaemia), NSAIDs, diuretics, or CYP3A4 inducers/inhibitors, as they may alter effects or increase risks.

• Monitoring: Regular blood pressure, potassium, and kidney function checks are advised. Monitor for signs of low blood pressure, especially when starting or changing doses.

• Consult your doctor for any underlying conditions or if you are elderly or have heart failure.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

Can I take potassium supplements with Losartan 50mg & Amlodipine 5mg Tablets IP?

Losartan 50mg & Amlodipine 5mg Tablets IP can cause high levels of potassium in the blood, leading to hyperkalaemia. Hence, it is not recommended to use potassium supplements along with Losartan 50mg & Amlodipine 5mg Tablets IP. However, consult your doctor if you are already taking other medicines before starting Losartan 50mg & Amlodipine 5mg Tablets IP.

Can I stop using Losartan 50mg & Amlodipine 5mg Tablets IP when my symptoms are relieved?

Do not stop using Losartan 50mg & Amlodipine 5mg Tablets IP even if you feel better. It should be used exactly as prescribed by your doctor to prevent symptom recurrence and disease progression.

Can I stop taking Losartan 50mg & Amlodipine 5mg Tablets IP when my blood pressure is under control?

You should inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Based on your current readings, your doctor may decide to adjust the dosage rather than advise discontinuing it altogether.

For how long do I need to take Losartan 50mg & Amlodipine 5mg Tablets IP?

The duration you take Losartan 50mg & Amlodipine 5mg Tablets IP depends on your health needs and blood pressure control. Typically, high blood pressure requires ongoing treatment. Your doctor will carefully track your progress and determine the appropriate duration for continuing the medication. It's essential not to stop taking Losartan 50mg & Amlodipine 5mg Tablets IP without consulting your doctor first, as they will adjust your treatment plan accordingly.

What kind of diet should I follow?

Maintain a balanced diet by focusing on natural, wholesome foods such as fresh fruits, vegetables, whole grains, low-fat or fat-free dairy products, and lean protein sources like poultry, fish, legumes, nuts, and seeds. Incorporating beans and lentils is also highly beneficial. Be mindful of your sodium intake to better manage blood pressure. Strive for variety in your meals to ensure you receive all essential nutrients. Following this approach supports overall health and well-being. If you have particular dietary needs or restrictions, consult a healthcare professional or registered dietitian for personalised advice.