Product Description

Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. It is a combination medication typically used when a single agent fails to control blood pressure adequately. Hypertension is a chronic condition where the force of blood against artery walls is excessively high, increasing the risk of heart diseases such as heart attack and stroke.

Uses

• Management of hypertension (high blood pressure).

• Reduction of stroke risk in hypertensive patients.

How it works

This tablet is a combination of Losartan (an angiotensin II receptor antagonist) and Hydrochlorothiazide (a thiazide diuretic).

• Losartan blocks angiotensin II receptors, relaxing and widening blood vessels to improve blood flow and lower blood pressure.

• Hydrochlorothiazide reduces excess salt and water absorption, preventing fluid retention and further aiding blood pressure reduction.

• Together, they effectively lower blood pressure and reduce the risks of stroke, heart attack, and edema.

Benefits

• Effectively treats high blood pressure when monotherapy is insufficient.

• Reduces the risk of stroke and cardiovascular events.

• Helps prevent fluid overload and related complications.

How to use

• Take the tablet whole with water; do not crush, split, or chew it.

• Take at the same time each day, with or without food, as prescribed by your doctor.

• Your doctor may adjust the dose based on your response. Do not stop without medical advice.

Side Effects

Common side effects may include:

• Dizziness

• Feeling tired

• Nausea

• Diarrhoea

• Dehydration

• Back pain

• Cold/flu symptoms

Serious side effects (seek immediate medical help):

• Hyperkalaemia (high potassium levels; symptoms: muscle weakness, irregular heartbeat)

• Electrolyte imbalances (e.g., low potassium, sodium)

• Gout or increased uric acid

• Allergic reactions (e.g., rash, swelling)

• Severe hypotension (low blood pressure)

• Kidney function changes

Report any persistent or severe symptoms to your doctor.

Safety Advice

• Alcohol: Avoid alcohol, as it may cause unpleasant side effects like drowsiness, dizziness, and liver damage.

• Pregnancy and Breastfeeding: Not recommended during pregnancy, as it may harm the fetus. Consult your doctor; use only if the benefits outweigh the risks. Not advised while breastfeeding.

• Kidney Conditions: Not recommended for severe chronic kidney disease, as safety and efficacy are not established. Use with caution in mild impairment.

• Contraindications: Do not use if you have anuria (inability to urinate), hypersensitivity to ARBs, sulfonamides, or thiazides, or severe hypotension.

• Drug Interactions: Inform your doctor about medications like potassium supplements (risk of hyperkalaemia), lithium, NSAIDs, or ACE inhibitors, as they may alter effects or increase risks.

• Monitoring: Regular blood pressure, electrolyte, potassium, and renal function checks are advised. Monitor for signs of dehydration or electrolyte issues.

• Consult your doctor if you have liver disease, diabetes, or are elderly.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP?

Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.

How does Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP work?

Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan, an angiotensin receptor blocker, relaxes and widens blood vessels to improve blood flow throughout the body. Hydrochlorothiazide, a diuretic, reduces excess salt absorption to prevent fluid retention. Together, they lower blood pressure and prevent the risk of stroke, heart attack, and oedema (fluid overload).

Can I stop taking Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP when my blood pressure is under control?

You should consult your doctor and monitor your blood pressure for at least two weeks before discontinuing the medication. Based on your current blood pressure readings, your doctor may adjust the dosage rather than recommend stopping it entirely.

For how long can Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP be taken?

Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP can be safely taken as long as your doctor has prescribed it to you. High blood pressure is a chronic condition, and you should not suddenly stop treatment without consulting your doctor.

What should I do if I miss a dose of Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP?

In case you have missed a dose of Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP, you are advised to take it as soon as you remember. Avoid missing a dose, but if it's nearly time for your next dose, do not take a double dose to make up for the missed one. Take only one dose; taking a double dose of Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP will lead to low blood pressure.

Can I take Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP in pregnancy?

It is not recommended to take Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP if you are pregnant, as it can damage the unborn baby (may lead to fetal toxicity).

Can Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP cause increased blood potassium levels?

Yes, prolonged intake of Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP can cause an increase in blood potassium level. So, patients taking Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP should avoid taking supplements and food rich in potassium to avoid any unpleasant side effects.

Can the use of Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP cause dizziness?

Yes, Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP. If you experience dizziness or lightheadedness, rest for a while until you feel better.

Are there any specific contraindications associated with Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP?

You should not take Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassiumIf you have conditions such as allergies, asthma, lupus (an autoimmune disease), diabetes, anuria (reduced or absent urine production), or are pregnant in your second or third trimester. Besides this, avoid using Losartan Potassium 50mg & Hydrochlorothiazide 12.5mg Tablets IP (in case of diabetes) with aliskiren (a blood pressure medicine) as it can lead to a life-threatening condition.