Product Description

Metoprolol Succinate 50 mg PR & Amlodipine 5 mg Tablets IP is a combination antihypertensive medication used in the treatment of high blood pressure (hypertension) and related cardiovascular conditions in adults. Hypertension is a chronic condition in which elevated blood pressure increases the risk of heart attack, stroke, heart failure, and kidney disease.

Together, these dual-action therapy provides effective blood pressure control and are often prescribed when monotherapy is insufficient.

Uses

• Treatment of hypertension (high blood pressure)
  

• Reduction of cardiovascular risk, such as heart attack and stroke
  

• Management of blood pressure in patients with associated cardiac conditions, as advised by a physician
  
  

How it Works

Metoprolol Succinate 50 mg PR & Amlodipine 5 mg Tablets IP work through complementary mechanisms:

• Metoprolol Succinate (50 mg PR): A beta-1 selective blocker that slows the heart rate and reduces the force of heart contractions, leading to decreased cardiac output and lower blood pressure. The prolonged-release formulation ensures sustained blood pressure control over 24 hours.
• Amlodipine (5 mg): Blocks calcium channels in blood vessel walls, causing vasodilation and reduced vascular resistance.

Together, they provide additive antihypertensive effects by targeting both cardiac output and vascular tone.

Benefits

• Effectively lowers systolic and diastolic blood pressure
  

• Reduces the risk of heart attack, stroke, and other cardiovascular events
  

• Prolonged-release formulation ensures steady, once-daily blood pressure control
  

• Improves patient compliance with convenient dosing
  

• Addresses both heart rate and blood vessel resistance
  
  

How to Use

Take Metoprolol Succinate 50 mg PR & Amlodipine 5 mg Tablets IP exactly as prescribed by your doctor. Swallow the tablet whole with water. Do not crush, chew, or break the tablet, as it is a prolonged-release formulation.

The tablet can be taken with or without food. Take it at the same time each day for best results. Do not stop the medication abruptly without medical advice.

Side Effects

Common side effects may include:

• Dizziness or lightheadedness
  

• Fatigue or weakness
  

• Slow heart rate
  

• Headache
  

• Ankle or foot swelling
  

• Flushing
  

• Nausea
  

Less common/serious side effects:

• Excessive drop in blood pressure
  

• Bradycardia (very slow heart rate)
  

• Shortness of breath
  

• Allergic reactions (rash, swelling)
  

If side effects persist or worsen, consult your doctor immediately.

Safety Advice

• Alcohol: Avoid alcohol, as it may increase dizziness and the risk of low blood pressure
  

• Pregnancy and Breastfeeding: Not recommended during pregnancy unless clearly advised by a doctor. Use with caution during breastfeeding
  

• Medical Conditions: Inform your doctor if you have asthma, heart block, heart failure, liver or kidney disease, diabetes, or thyroid disorders
  

• Other Medicines: Inform your doctor about all other medicines you are taking to avoid interactions
  

• Monitoring: Regular monitoring of blood pressure and heart rate is advised
  

• Do not stop abruptly: Sudden discontinuation may worsen heart conditions or cause rebound hypertension
  
  

Storage Conditions

• Store below 30°C (86°F)
  

• Protect from light and moisture
  

• Keep out of reach of children
  
  

FAQs

What is the use of Metoprolol Succinate 50 mg PR & Amlodipine 5 mg Tablets IP?

It is used to treat high blood pressure and reduce the risk of cardiovascular complications such as heart attack and stroke.

Can this medicine cause a slow heart rate?

Yes, metoprolol may cause a slow heart rate. Mild changes are usually not serious, but consult your doctor if symptoms like dizziness or fatigue occur.

Can I stop taking this medicine when my blood pressure is controlled?

No. Do not stop taking the medicine without consulting your doctor, as blood pressure may rise again.

Does this medicine cause swelling?

Amlodipine may cause ankle or foot swelling in some patients. Inform your doctor if swelling is persistent.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is nearly time for the next dose, skip the missed dose. Do not take a double dose.

Is it safe for long-term use?

Yes, it is generally safe for long-term use when taken as prescribed and monitored regularly by a doctor.