Product Description

Norfloxacin 400mg Tinidazole 600mg Tablets are a combination antibiotic medication used to treat bacterial and protozoal infections, such as diarrhea, dysentery, and stomach infections.

Dysentery is an intestinal infection causing severe diarrhea with blood, often lasting 3-7 days. Diarrhea involves frequent, loose, watery stools and can be acute (resolving in 1-2 days) or chronic (lasting 4 weeks or more).

This combination is effective against susceptible organisms causing gastrointestinal infections. Norfloxacin, a fluoroquinolone, inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and repair, leading to bacterial cell death. Tinidazole, a nitroimidazole, damages DNA in anaerobic bacteria and protozoa, resulting in their elimination. Together, they provide broad-spectrum activity against the causative pathogens.

Uses

• Treatment of Diarrhea (bacterial or protozoal causes)

• Treatment of Dysentery

• Treatment of Stomach infections (e.g., gastrointestinal infections from susceptible organisms).

How it works

Norfloxacin 400mg & Tinidazole 600mg Tablets combine two antibiotics: Norfloxacin and Tinidazole. Norfloxacin works by inhibiting DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and repair, which leads to bacterial cell death. Tinidazole targets anaerobic bacteria and protozoa by interfering with their DNA synthesis, causing cell destruction. This dual mechanism helps eradicate the infection by killing or inhibiting the growth of the responsible bacteria and parasites.

Benefits

Norfloxacin 400mg, Tinidazole 600mg Tablets are effective for treating gastrointestinal infections by addressing both bacterial and protozoal causes. Norfloxacin helps control bacterial growth, while Tinidazole eliminates protozoa, providing comprehensive relief from symptoms like diarrhea, abdominal pain, and fever. When taken as a full course, it helps eradicate the infection, prevents recurrence, and improves digestive health, making it suitable for conditions like dysentery and bacterial diarrhea.

How to use

Take Norfloxacin 400mg, Tinidazole 600mg Tablets as directed by your doctor, usually with a full glass of water. Swallow the tablet whole; do not crush, break, or chew it. It can be taken with or without food, but for the best results, follow the prescribed timing and complete the full course even if symptoms improve.

Side Effects

Common side effects of Norfloxacin 400mg, Tinidazole 600mg Tablets may include:

• Nausea

• Dryness of mouth

• Stomach upset

• Headache

• Metallic taste or change in taste

• Loss of appetite

• Weakness

• Skin rash or itching

These side effects are usually mild and temporary. If they persist or worsen, or if you experience severe symptoms like neurological issues (e.g., dizziness, seizures), allergic reactions (e.g., swelling, rash), or gastrointestinal bleeding, seek medical attention immediately. Long-term use may increase the risk of antibiotic resistance or secondary infections.

Safety Advice

• Alcohol: Avoid alcohol while taking Norfloxacin 400mg and Tinidazole 600mg Tablets, as it can cause stomach irritation and increase the risk of side effects like nausea or disulfiram-like reactions with Tinidazole. Consult your doctor for advice.

• Pregnancy and Breastfeeding: Norfloxacin is classified as a Pregnancy Category C drug, and Tinidazole has potential risks; both should be used only if the benefits outweigh the risks and under medical supervision. They may pass into breast milk, so avoid use while breastfeeding or discuss alternatives with your doctor.

• Other Precautions: Use with caution in patients with kidney, liver, or neurological disorders, as dosage adjustments may be needed. Inform your doctor of all medications, as interactions can occur (e.g., with antacids or blood thinners). This combination is not suitable for viral infections and should be used judiciously to prevent resistance.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of Norfloxacin 400mg Tinidazole 600mg Tablet?

Norfloxacin 400mg Tinidazole 600mg Tablet is used to treat diarrhoea, dysentery and stomach infections.

How does Norfloxacin 400mg Tinidazole 600mg Tablet work?

Norfloxacin 400mg Tinidazole 600mg Tablet is a combination of two antibiotics, Norfloxacin and Tinidazole, primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin prevents bacterial cell division, thereby killing the bacteria. Tinidazole destroys parasites causing infections by damaging their DNA. Both components effectively combat the disease through their bactericidal action, eliminating bacteria.

Can Norfloxacin 400mg and Tinidazole 600mg tablets cause serious side effects?

Yes, Norfloxacin 400mg Tinidazole 600mg Tablet may cause minor skin rashes or reactions. In case you are experiencing skin rashes or any such allergic reactions, consult a doctor and stop taking Norfloxacin 400mg Tinidazole 600mg Tablet.

Can Norfloxacin 400mg Tinidazole 600mg Tablet be taken for stomach pain?

No, Norfloxacin 400mg Tinidazole 600mg Tablet is a combination of two antibiotic drugs, which help resolve moderate to severe infections of the stomach. This medicine is not a painkiller. However, completing a full course of Norfloxacin 400mg Tinidazole 600mg Tablet may bring relief to discomfort and stomach pain caused due to infections.

Are there any specific contraindications associated with the use of Norfloxacin 400mg Tinidazole 600mg Tablet?

Norfloxacin 400mg and Tinidazole 600mg tablets are considered harmful for patients with a known allergy to norfloxacin, tinidazole, or any other ingredient in the medication. It should generally be avoided in patients with a history of tendinitis (tendon inflammation) or tendon rupture, as well as in those with certain neurological disorders.

Can I stop taking Norfloxacin 400mg, Tinidazole 600mg Tablet when my symptoms are relieved?

Do not discontinue Norfloxacin 400mg and Tinidazole 600mg tablets even if you feel better, as this antibiotic requires a full course of treatment. Consult your doctor for the best guidance and follow their advice.