Product Description

Ofloxacin 200mg & Ornidazole 500mg Tablet belongs to the group of medicines called antibiotics, used to treat various bacterial and protozoan infections. It is effective for urinary tract infections, peritonitis, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, intra-abdominal infections, and infections during surgical procedures. It is also used to treat diarrhea caused by mixed bacterial and protozoan infections in adults.

Ofloxacin is a fluoroquinolone that inhibits DNA gyrase, an enzyme necessary for bacterial DNA replication and repair. Ornidazole, a nitroimidazole, works by damaging DNA in anaerobic bacteria and protozoa, leading to cell death. Together, this combination provides broad-spectrum activity against susceptible organisms.

Uses

• Treatment of Bacterial infections (e.g., urinary tract, skin, respiratory, and intra-abdominal infections)

• Treatment of Protozoan infections (e.g., associated with diarrhea or vaginal infections)

• Management of Mixed infections causing diarrhea in adults.

How it works

Ofloxacin 200mg & Ornidazole 500mg Tablet is a combination of two antibiotics: Ofloxacin and Ornidazole. Ofloxacin works by inhibiting DNA gyrase, an enzyme essential for bacterial DNA replication, transcription, and repair, thereby preventing bacterial growth. Ornidazole targets anaerobic bacteria and protozoa by interfering with their DNA synthesis, causing cell death. This dual action helps effectively treat a wide range of infections by targeting both aerobic and anaerobic pathogens.

Benefits

Ofloxacin 200mg & Ornidazole 500mg Tablet offers broad-spectrum antibacterial and antiprotozoal activity, making it effective for treating mixed infections that are difficult to manage with a single agent. It helps reduce symptoms like pain, inflammation, and discharge in infections, promotes faster recovery, and is particularly useful in surgical prophylaxis or gastrointestinal infections. By combining the strengths of Ofloxacin and Ornidazole, it improves treatment outcomes while minimizing the risk of resistance when used appropriately.

How to use

Swallow Ofloxacin 200mg & Ornidazole 500mg Tablet as a whole with a glass of water; do not chew, break, or crush it. It can be taken with or without food, but taking it with food may help reduce stomach upset. Follow your doctor's instructions on dosage and duration, and complete the full course even if symptoms improve to prevent resistance.

Side Effects

Common side effects of Ofloxacin 200mg & Ornidazole 500mg Tablet may include:

• Nausea

• Vomiting

• Abdominal pain

• Headache

• Dizziness

• Other potential side effects: Diarrhea, rash, or metallic taste (less common)

These side effects are usually mild and resolve on their own. If they persist, worsen, or include severe symptoms like allergic reactions (e.g., swelling, difficulty breathing), tendon pain, or neurological issues, stop the medication and consult a doctor immediately. Long-term use may lead to antibiotic resistance or secondary infections.

Safety Advice

• Alcohol: Avoid alcohol while taking Ofloxacin 200mg & Ornidazole 500mg Tablet, as it can increase the risk of side effects like dizziness, nausea, or disulfiram-like reactions with Ornidazole.

• Pregnancy and Breastfeeding: This combination is generally not recommended during pregnancy (Category C for Ofloxacin) unless the benefits outweigh the risks, as it may affect fetal development. It may also pass into breast milk, so consult your doctor before use if breastfeeding.

• Other Precautions: Use with caution in patients with kidney or liver impairment, as dosage adjustments may be needed. Inform your doctor of any history of seizures, tendon disorders, or allergies. This medicine can interact with certain drugs (e.g., antacids or blood thinners), so disclose your full medication list. Avoid prolonged exposure to sunlight, as Ofloxacin increases photosensitivity.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

How should I take Ofloxacin and Ornidazole?

Take this medication as directed by your doctor, usually with food to minimize stomach upset. Swallow the tablet whole; do not alter it. Dosage and duration depend on your specific infection and health. 

What happens if I miss a dose?

If a dose is missed, take it when you remember. If it's near the next dose time, skip the missed one and continue your schedule. Do not take extra time to catch up. 

Can I stop taking the medicine when I feel better?

No, complete the entire prescribed course even if your symptoms improve, as stopping early can cause the infection to return and become harder to treat. 

Should I avoid alcohol while taking this medicine?

Yes, avoid alcohol as it can increase side effects like dizziness and drowsiness. 

Is this medicine safe during pregnancy or breastfeeding?

Use during pregnancy is generally not advised due to potential harm to the baby. Consult your doctor to discuss risks and benefits. It's also not recommended while breastfeeding as the drugs can pass into breast milk. 

What precautions should I take?

Avoid driving or operating machinery if you feel dizzy or sleepy. Do not take this medication if you are allergic to Ofloxacin, Ornidazole, or similar antibiotics. Be aware of the risk of tendon rupture with Ofloxacin and report any tendon pain or swelling to your doctor. Inform your doctor of any history of heart, kidney, or liver issues, epilepsy, diabetes, or myasthenia gravis.