Product Description

Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP belong to a class of medications called antihypertensives, primarily used to treat high blood pressure (hypertension). Hypertension is a chronic condition characterised by elevated blood pressure against artery walls, increasing the risk of heart attack, heart failure, stroke, irregular heartbeat, and other complications.

This combination contains two active ingredients:

• Olmesartan medoxomil, an angiotensin II receptor blocker (ARB), inhibits the hormone angiotensin II, causing relaxation and widening of constricted blood vessels. This improves blood flow and reduces the workload on the heart.

• Hydrochlorothiazide, a thiazide diuretic ("water pill") that helps remove excess water and electrolytes from the body, reducing fluid overload and lowering blood pressure.

Together, they effectively lower blood pressure and reduce fluid retention.

Do not use potassium supplements or salt substitutes unless advised by your doctor. Rarely, this medication may cause muscle problems (rhabdomyolysis) leading to kidney failure. If you experience unexplained muscle pain, weakness, or dark urine, seek medical attention immediately.

Do not stop this medication abruptly without consulting your doctor, as it may cause blood pressure to rise and increase the risk of heart disease or stroke. Inform your doctor if you have kidney, liver, or heart disease, or diabetes.

Uses

Treatment of hypertension (high blood pressure)

How it works

Olmesartan medoxomil blocks angiotensin II receptors, relaxing blood vessels and improving blood flow. Hydrochlorothiazide increases urine output, removing excess fluid and electrolytes. Together, they lower blood pressure and reduce fluid overload.

Benefits

• Effective blood pressure control to reduce the risk of cardiovascular events

• Combination therapy targets blood pressure through complementary mechanisms

• Helps reduce fluid retention and associated symptoms

• May improve heart function by reducing vascular resistance and volume overload

How to use

Take the tablet whole with water, with or without food. Do not crush, break, or chew. Follow your doctor’s instructions regarding dosage and timing.

Side Effects

• Stuffy nose or sore throat

• Nausea

• Upset stomach

• Headache

• Elevated uric acid levels (may worsen gout)

• Diarrhea

• Electrolyte imbalances (e.g., low potassium, sodium)

• Dehydration

• Dizziness or lightheadedness

• Low blood pressure (hypotension)

Safety Advice

• Avoid alcohol while taking this medication to prevent increased dizziness, drowsiness, and liver damage.

• Inform your doctor if you have kidney or liver disease, heart problems, or diabetes.

• Do not take potassium supplements or salt substitutes without medical advice.

• Monitor blood pressure regularly.

• Do not stop medication abruptly without consulting your doctor.

• Inform your doctor before surgery, as the medication may need to be temporarily stopped.

Storage Conditions

• Store at a temperature below 30°C (86°F).

FAQs

What is the use of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP?

It is used to treat high blood pressure (hypertension) to reduce the risk of heart attack, stroke, and other complications.

How does Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP work?

Olmesartan relaxes blood vessels by blocking angiotensin II receptors, and hydrochlorothiazide removes excess fluid by increasing urine output. Together, they lower blood pressure.

Does intake of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP affect fertility?

It is unlikely to affect fertility. However, hydrochlorothiazide may cause erectile dysfunction in some men. Consult your doctor for advice.

What should I do if I miss a dose of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP?

In case you have missed a dose of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both doses together. Take only the prescribed single dose; a double dose of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP may cause low blood pressure.

How long can Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP be taken?

Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP can be safely taken as long as your doctor has prescribed it to you. High blood pressure is a lifelong condition, and you should not stop taking Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP abruptly without consulting your doctor. Discontinuing this medication may cause elevated blood pressure, increasing the future risk of heart attack and stroke.

Can I stop taking Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP when my blood pressure is under control?

No, you should inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Based on your current readings, your doctor may adjust the dosage instead of advising complete discontinuation.

Can I take Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP before a surgery?

Inform your doctor before surgery if you are taking Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP, as the medicine may need to be stopped to prevent a drop in blood pressure during the procedure.

Can I feel dizzy after taking Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP?

Dizziness is a common side effect of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP. If you feel dizzy, avoid driving or operating heavy machinery..

Does taking Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP lead to weight gain?

Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP may cause weight gain in some people, but it's not common. This may occur as the medicine can cause fluid retention, elevated sodium levels, or increased appetite. If you experience noticeable weight gain, consult your doctor for proper guidance.

What are the serious side effects of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP?

In rare cases, Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP may cause serious side effects like bladder pain, bloating, blurred vision, chest pain, increased urination, or unusual weight gain or loss. Not everyone may experience these side effects, but if you do, contact your doctor right away.

Do Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP have any effect on fertility or sexual health?

Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP are unlikely to affect fertility in either men or women. However, in some cases, diuretics like hydrochlorothiazide may cause erectile dysfunction. For personalised guidance, consult your doctor.

Can I take Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP with food?

You may take Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP with or without food, as directed by your doctor.

What are the common side effects of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP?

Common side effects of Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP include a stuffy nose, sore throat, nausea, upset stomach, headache, high uric acid levels, diarrhoea, electrolyte imbalances, dehydration, dizziness, and low blood pressure. These side effects are usually mild and tend to improve on their own. However, if they continue or get worse, you should seek medical advice from your doctor.

Can pregnant women take Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP?

Olmesartan Medoxomil 20mg & Hydrochlorothiazide 12.5mg Tablets IP is not recommended during pregnancy, as it is classified as a Category D medication. This means it may be harmful to the fetus and could affect the baby’s development. If you are pregnant or planning to conceive, consult your doctor to discuss safer treatment options.