Product Description

Silodosin 8 mg & Dutasteride 0.5 mg Capsules IP is a combination medicine used for the treatment of benign prostatic hyperplasia (BPH) in adult men. Benign prostatic hyperplasia is a non-cancerous enlargement of the prostate gland that commonly occurs with aging and leads to urinary symptoms such as difficulty in passing urine, weak urine stream, frequent urination, urgency, and incomplete bladder emptying.

This combination contains Silodosin, a selective alpha-1 adrenergic receptor blocker, and Dutasteride, a 5-alpha reductase inhibitor. Silodosin relaxes the smooth muscles of the prostate, bladder neck, and urethra, providing rapid relief from urinary obstruction. Dutasteride reduces the size of the enlarged prostate by blocking the conversion of testosterone to dihydrotestosterone (DHT), the hormone responsible for prostate growth.

Together, Silodosin 8 mg & Dutasteride 0.5 mg Capsules IP offer both fast symptom relief and long-term disease control, reducing the risk of acute urinary retention and the need for prostate surgery. This medicine is intended for adult men only and does not cure prostate cancer.

Uses

Silodosin 8 mg & Dutasteride 0.5 mg Capsules IP are used for:

• Treatment of benign prostatic hyperplasia (enlarged prostate)
  

• Relief of lower urinary tract symptoms (LUTS) such as weak stream, hesitancy, urgency, nocturia, and incomplete bladder emptying
  

• Reduction of prostate size and prevention of disease progression
  

• Lowering the risk of acute urinary retention and prostate-related surgery
  
  

How it works

Silodosin 8 mg & Dutasteride 0.5 mg Capsules IP work through complementary mechanisms:

• Silodosin (8 mg): Selectively blocks alpha-1 receptors in the prostate and bladder neck, relaxing smooth muscle tone and reducing urinary resistance. This improves urine flow and relieves symptoms quickly.
  

• Dutasteride (0.5 mg): Inhibits both type-1 and type-2 5-alpha reductase enzymes, significantly reducing DHT levels. This leads to a gradual shrinkage of the prostate gland and prevents further enlargement.
  

The combination targets both the dynamic component (muscle tension) and static component (prostate size) of BPH for effective long-term management.

Benefits

Silodosin 8 mg & Dutasteride 0.5 mg Capsules IP provide comprehensive benefits in men with BPH:

• Rapid improvement in urinary symptoms and urine flow
  

• Gradual reduction in prostate size over time
  

• Decreased frequency of nighttime urination and urgency
  

• Reduced risk of acute urinary retention and need for surgery
  

• Improved quality of life with sustained symptom control
  
  

How to use

Take Silodosin 8 mg & Dutasteride 0.5 mg Capsules IP exactly as prescribed by your doctor

• Take the capsule once daily with food, preferably at the same time each day
  

• Swallow the capsule whole with water
  

• Do not crush, chew, or open the capsule
  

• Continue treatment for the duration advised by your doctor
  
  

Do not stop the medication without medical advice, as symptoms may worsen.

Side Effects

Common side effects may include:

• Ejaculation disorders (reduced or absent semen during orgasm)
  

• Dizziness or lightheadedness
  

• Decreased libido
  

• Erectile dysfunction
  

• Nasal congestion
  

• Breast tenderness or enlargement
  
  

Most side effects are mild and improve with continued use. Consult your doctor if symptoms persist or become bothersome.

Safety Advice

• Alcohol: Limit alcohol intake, as it may increase dizziness or low blood pressure
  

• Pregnancy: Dutasteride is contraindicated in pregnancy; women who are pregnant or may become pregnant should not handle capsules
  

• Blood donation: Avoid donating blood during treatment and for at least 6 months after stopping the medicine
  

• Driving: Use caution while driving or operating machinery, especially during initial treatment
  

• Medical conditions: Inform your doctor if you have low blood pressure, liver disease, or kidney problems
  

Regular prostate examinations and PSA monitoring are recommended during long-term therapy.

Storage Conditions

• Store below 30°C (86°F)
  

• Protect from light and moisture
  

• Keep out of reach of children
  
  

FAQs

What are Silodosin & Dutasteride Capsules IP used for?

It is used to treat symptoms of benign prostatic hyperplasia (BPH) in men by improving urine flow and reducing prostate size.

How does this combination help in BPH?

Silodosin provides quick relief by relaxing prostate muscles, while Dutasteride reduces prostate growth by lowering DHT levels.

Does this medicine cure an enlarged prostate?

No, it does not cure BPH, but it effectively manages symptoms and slows disease progression.

How long does it take to show benefits?

Symptom relief may begin within days due to Silodosin, while prostate size reduction from Dutasteride may take several months.

Can women take this medicine?

No. This medicine is intended only for men and should not be used by women or children.

Can this medicine affect sexual function?

Yes, it may cause ejaculation disorders or reduced libido in some men. These effects are usually reversible after stopping treatment.