Product Description

Sodium Valproate 333mg & Valproic Acid 145mg Tablet IP belongs to a group of medicines known as antiepileptics (anticonvulsants). It is primarily used in the management of epilepsy (seizure disorders). This medicine is also prescribed in certain patients for the treatment of mood disorders and for the prevention of migraine headaches.

Epilepsy is a neurological condition characterised by abnormal electrical activity in the brain, leading to seizures that may affect consciousness, movement, or sensation. Valproate 333mg & Valproic Acid 145mg Tablet IP helps stabilise this abnormal brain activity and reduces the frequency and severity of seizures.

This formulation contains sodium valproate and valproic acid, which work together to control excessive nerve impulses in the brain and provide a calming effect on the nervous system. It should be used strictly under medical supervision.

Uses

Valproate & Valproic Acid Tablets IP are used for:

• Treatment of epilepsy and seizure disorders
  

• Management of certain mood disorders (as prescribed)
  

• Prevention of migraine headaches
  

How it works

Valproate 333mg & Valproic Acid 145mg Tablet IP is a combination of two active ingredients:

• Sodium Valproate
  

• Valproic Acid
  

These medicines act by reducing abnormal electrical activity in the brain. They increase the levels of gamma-aminobutyric acid (GABA), a neurotransmitter that suppresses excessive nerve firing. This helps stabilise brain activity, prevents seizure episodes, and produces a calming effect on the nervous system.

Benefits

• Helps control partial and generalised seizures
  

• Effective in various seizure types, including absence, myoclonic, and tonic-clonic seizures
  

• Reduces abnormal nerve activity in the brain
  

• May help prevent migraine attacks
  

• Supports mood stabilisation in selected patients
  

How to use

• Take Valproate & Valproic Acid Tablets IP exactly as prescribed by your doctor
  

• Swallow the tablet whole with a glass of water
  

• Do not crush, chew, or break the tablet
  

• It may be taken with food or 1 hour before meals, as advised by your doctor
  

• Do not stop the medicine abruptly without medical advice
  

Side Effects

Common side effects may include:

• Headache
  

• Nausea or vomiting
  

• Diarrhoea
  

• Sleepiness or drowsiness
  

• Impaired coordination
  

• Weight gain
  

• Hair loss
  

• Irregular menstrual cycles
  

• Lack of interest or low mood
  

If any side effects persist or worsen, consult your doctor promptly.

Safety Advice

• Alcohol: Avoid alcohol consumption, as it may increase seizure risk and drowsiness
  

• Pregnancy: This medicine belongs to Pregnancy Category D and may cause serious birth defects. Avoid use during pregnancy unless clearly advised by a doctor
  

• Breastfeeding: Use with caution; consult your doctor before use
  

• Bleeding Risk: May lower platelet count, increasing the risk of bleeding or bruising
  

• Regular Monitoring: Liver function tests, blood counts, and weight monitoring may be required during treatment
  

Storage Conditions

• Store below 30°C (86°F)
  

• Protect from light and moisture
  

• Keep out of reach of children
  

FAQs

What is Valproate 333mg & Valproic Acid 145mg Tablet IP used for?

It is mainly used to treat epilepsy and seizure disorders and may also be prescribed for mood disorders and migraine prevention.

How does this medicine control seizures?

It increases gamma-aminobutyric acid (GABA) levels in the brain, which helps suppress abnormal nerve activity and stabilise brain signals.

Can I stop taking this medicine if I feel better?

No. Stopping suddenly may worsen seizures. Always consult your doctor before discontinuation.

Does it increase the risk of bleeding?

Yes, it may reduce platelet levels. Inform your doctor if you notice unexplained bruising or bleeding.

Can it cause weight gain?

Yes, increased appetite and weight gain may occur. Maintaining a healthy diet and regular exercise is advised.

Can aspirin be taken with this medicine?

Use caution. Valproate may increase the effects of aspirin. Consult your doctor before combining these medicines.