Product Description

Tamsulosin Hydrochloride (Modified Release) 0.4 mg & Dutasteride 0.5 mg Tablets are a combination medicine used in men for the treatment of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland. BPH commonly occurs due to increased production of the hormone dihydrotestosterone (DHT), leading to compression of the urethra and difficulty in passing urine.

As the prostate enlarges, it may cause urinary symptoms such as a weak urine stream, frequent urination, urgency, nocturia (night-time urination), and incomplete bladder emptying. This combination therapy helps relieve these symptoms and improves urinary flow. However, it does not cure prostate cancer.

The formulation contains Tamsulosin, an alpha-1 adrenergic blocker that relaxes the smooth muscles of the prostate and bladder neck, and Dutasteride, a 5-alpha reductase inhibitor that reduces prostate size by lowering DHT levels. Together, they provide both immediate symptom relief and long-term disease control.

Uses

Tamsulosin Hydrochloride & Dutasteride Tablets are used for:

• Treatment of benign prostatic hyperplasia (BPH)
  

• Relief of urinary symptoms such as weak stream, urgency, frequency, and nocturia
  

• Reduction in the risk of acute urinary retention
  

• Decreasing the need for prostate-related surgery
  
  

How it works

This medicine works through the combined action of two drugs:

• Tamsulosin Hydrochloride (0.4 mg): Relaxes the smooth muscles of the prostate and bladder neck by blocking alpha-1 receptors, thereby reducing resistance to urine flow and improving urination.
  

• Dutasteride (0.5 mg): Inhibits the enzyme 5-alpha reductase, reducing the conversion of testosterone to dihydrotestosterone (DHT). Lower DHT levels lead to gradual shrinkage of the enlarged prostate.
  

Together, these actions improve urinary symptoms, reduce prostate size, and lower the risk of urinary complications associated with BPH.

Benefits

• Improves urine flow and reduces urinary obstruction
  

• Provides both short-term symptom relief and long-term prostate size reduction
  

• Reduces the risk of acute urinary retention
  

• Minimizes the likelihood of requiring prostate surgery
  

• Enhances the quality of life in men with BPH
  
  

How to use

• Take the tablet exactly as prescribed by your doctor
  

• Swallow the tablet whole with water
  

• Do not crush, chew, or break the tablet
  

• Take it at the same time each day, preferably after a meal
  

• Continue treatment regularly for the best results
  

Do not stop the medication without consulting your doctor, even if symptoms improve.

Side Effects

Common side effects may include:

• Decreased sexual desire (libido)
  

• Difficulty with ejaculation
  

• Erectile dysfunction
  

• Breast tenderness or enlargement (gynecomastia)
  

• Dizziness or light-headedness
  

These side effects are usually mild, but consult your doctor if they persist or worsen.

Safety Advice

• Alcohol: Avoid alcohol, as it may increase dizziness and low blood pressure
  

• Pregnancy: Not intended for use in women; exposure during pregnancy may harm a male fetus
  

• Blood donation: Do not donate blood during treatment and for at least 6 months after stopping Dutasteride
  

• Eye surgery: Inform your doctor before cataract or glaucoma surgery
  

• Other medicines: Inform your doctor about all medications to avoid interactions
  

Regular medical follow-up is recommended to monitor prostate health.

Storage Conditions

• Store below 30°C (86°F)
  

• Protect from light and moisture
  

• Keep out of reach of children
  

FAQs

What is Tamsulosin Hydrochloride & Dutasteride used for?

It is used to treat benign prostatic hyperplasia (BPH) and relieve urinary symptoms caused by prostate enlargement.

How does this combination help in BPH?

Tamsulosin improves urine flow by relaxing prostate muscles, while Dutasteride reduces prostate size by lowering DHT levels.

Does this medicine cure prostate cancer?

No, it does not cure prostate cancer. It is only indicated for benign prostate enlargement.

Can this medicine cause sexual side effects?

Yes, reduced libido, ejaculation problems, and erectile dysfunction may occur in some patients.

Can elderly patients take this medicine safely?

Yes, it is commonly prescribed in elderly men, but regular monitoring is advised.

How long should this medicine be taken?

Treatment duration depends on your condition. BPH usually requires long-term therapy as advised by a doctor.

Is it safe to stop the medicine once symptoms improve?

No. Stopping the medicine abruptly may cause symptoms to return. Always consult your doctor before discontinuation.