Product Description

Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablets IP is a combination antihypertensive medication used primarily to treat hypertension (high blood pressure). Hypertension is a chronic condition where the force of blood against artery walls is consistently elevated, which can lead to complications like heart disease, stroke, or kidney problems. In some cases, fluid retention (edema) may occur as a side effect of high blood pressure or certain medications, causing swelling in areas like the hands, feet, or ankles. This tablet combines three drugs to lower blood pressure effectively, reducing the risk of cardiovascular events. It is available by prescription and should be used under medical supervision.

Uses

• Treatment of hypertension (high blood pressure), either alone or in combination with other therapies.

• Management of essential hypertension to reduce the risk of stroke, heart attack, and other complications.

• It may also be used for hypertension-associated conditions, as directed by a doctor, but not for treating edema alone.

How it works

Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablets IP is a fixed-dose combination of three antihypertensive agents:

• Telmisartan (40 mg): An angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking angiotensin II, a hormone that causes vasoconstriction, thus improving blood flow and reducing blood pressure.

• Amlodipine (5 mg): A calcium channel blocker that prevents calcium from entering heart and blood vessel cells, leading to vasodilation (widening of blood vessels) and easier blood flow.

• Hydrochlorothiazide (12.5 mg): A thiazide diuretic that increases urine production, removing excess salt and water from the body, which helps lower blood volume and blood pressure.

Together, they provide complementary effects: Telmisartan reduces vascular resistance, Amlodipine enhances vasodilation, and Hydrochlorothiazide promotes diuresis, leading to effective blood pressure control. Onset is typically within 2–4 hours for Amlodipine and Telmisartan, with full effects in 1–2 weeks.

Benefits

• Effective blood pressure control: Lowers systolic and diastolic pressure, reducing the risk of heart attack, stroke, and kidney damage.

• Comprehensive action: The combination addresses multiple pathways of hypertension, improving efficacy compared to single agents and minimizing fluid retention.

• Long-term management: Convenient once-daily dosing enhances adherence for chronic use, with studies indicating sustained benefits in reducing cardiovascular events.

How to use

Take Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablets IP exactly as prescribed by your doctor. Swallow the tablet whole with water, preferably at the same time each day, with or without food. Do not crush, break, or chew it. Continue regular monitoring of blood pressure and follow up with your doctor. If you miss a dose, take it as soon as you remember, but skip it if it's almost time for the next dose—do not double up.

Side Effects

Common side effects (usually mild and transient):

• Neurological: Sleepiness, headache, dizziness, tiredness.

• Cardiovascular: Palpitations, ankle swelling (due to fluid retention).

• Gastrointestinal: Stomach upset, upper abdominal pain.

• Other: Flushing.

If side effects persist or worsen, consult your doctor. Serious side effects, though rare, may include severe allergic reactions, electrolyte imbalances, or kidney issues.

Safety Advice

• Alcohol Interaction: Avoid alcohol, as it can worsen side effects like dizziness or dehydration from Hydrochlorothiazide.

• Pregnancy and Breastfeeding: This medication is contraindicated in pregnancy (especially the second and third trimesters due to risks of fetal harm from Telmisartan and Hydrochlorothiazide, with black box warnings. Use only if absolutely necessary and under strict medical supervision. It is excreted in breast milk, so consult your doctor before use during breastfeeding.

• Other Precautions: Use with caution in patients with kidney or liver diseases, as dose adjustments may be required (e.g., avoid in severe renal impairment). Monitor for electrolyte imbalances (e.g., low potassium), dehydration, or hyperkalemia (with Telmisartan). Not recommended for children or those with anuria (no urine output). Inform your doctor of all medications to avoid interactions (e.g., with NSAIDs or potassium supplements). Regular blood pressure and kidney function monitoring is advised.

• Lifestyle Advice: Follow a low-salt diet, exercise regularly, and monitor for symptoms like dizziness. Do not stop abruptly, as it may cause rebound hypertension.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

Can I stop taking Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet when my blood pressure is under control?

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

What should I do if I miss a dose of Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet?

In case you forget to take Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take an extra dose to compensate for a missed one.

For how long can Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet be taken?

Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions like high blood pressure are chronic, and you should not suddenly stop treatment without consulting your doctor.

Can the use of Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet cause dizziness?

Yes, Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet. If you experience dizziness or lightheadedness, rest until you feel better.

Are there any specific contraindications associated with Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet?

Yes, Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet is contraindicated in people with known allergy to any of the components of this medicine. It should not be used by individuals with severe kidney or liver impairment, those with anuria (little to no urine production), or women in their second or third trimester of pregnancy.

Can I take Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet on my own?

Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

What are the instructions for the storage and disposal of Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet?

Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet should be stored in a cool and dry place away from sunlight. Dispose of expired or unused medication safely and responsibly. Consult your pharmacist for guidance on proper disposal.

Can I feel dizzy after taking Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg Tablet?

Yes, Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet can cause dizziness. It is advised to avoid driving or operating any heavy machinery. Most of these side effects of Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Can I use Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet in pregnancy?

Telmisartan 40mg, Amlodipine 5mg & Hydrochlorothiazide 12.5mg  Tablet should not be taken during pregnancy. If you're already taking telmisartan and become pregnant, stop taking it immediately and contact your doctor right away. It is not suitable for people with severe kidney or liver issues, those with anuria (minimal or no urine output), or pregnant women in their second or third trimester.