Product Description

Ticagrelor 90 mg Tablet IP is an antiplatelet agent primarily used to prevent heart attacks and strokes in people at high risk of cardiovascular disease. It helps prevent blood clots in patients with acute coronary syndrome (ACS) - a condition where the heart muscle does not receive enough oxygen due to reduced blood flow. Ticagrelor is especially prescribed for patients who have had stents placed in the coronary arteries to keep them open. A heart attack occurs when a blood clot blocks blood flow to the heart. This blockage often results from the buildup of cholesterol, fat, and other substances forming plaque in the coronary arteries. Symptoms of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue, and difficulty breathing.

Uses

• Prevention of heart attack and stroke

• Management of acute coronary syndrome (ACS)

• Prevention of blood clots after stent placement in the coronary arteries

How it works

Ticagrelor is an antiplatelet agent that inhibits platelet aggregation by reversibly blocking the P2Y12 receptor on platelets. Platelets are blood cells that normally clump together to seal injuries in blood vessels. However, in narrowed arteries, platelets can form clots that block blood flow to the heart or brain, causing heart attacks or strokes. Ticagrelor reduces this risk by making platelets less likely to stick together.

Benefits

• Reduces the risk of heart attack and stroke in high-risk patients

• Prevents harmful blood clot formation in patients with acute coronary syndrome

• Helps maintain blood flow in patients with coronary stents

• Provides reversible platelet inhibition, allowing more flexible management around surgeries

How to use

• Tablet: Swallow whole with water. Do not crush, break, or chew the tablet.

• Orodispersible/Mouth-Dissolving Tablet: Place the tablet in your mouth and allow it to dissolve completely. Do not swallow whole. Avoid handling the tablet with wet hands.

Side Effects

Common side effects include:

• Dyspnea (shortness of breath)

• Chest tightness

• Blurred vision

• Nosebleeds

• Dizziness or lightheadedness, especially when standing up quickly

• Headache

• Bruising

• Diarrhea, indigestion, or constipation

• Increased uric acid levels, which may cause gout symptoms (joint pain and swelling)

• Excessive bleeding from cuts, wounds, or after surgery

• Bleeding gums or bleeding from the stomach lining (ulcers)

If you experience severe or uncontrollable bleeding, seek immediate medical attention.

Safety Advice

• Avoid alcohol or limit consumption, as it may increase dizziness and bleeding risk.

• Inform your doctor if you have any bleeding disorders, a history of stroke, stomach ulcers, or liver disease.

• Ticagrelor is not recommended during pregnancy unless the benefits outweigh the risks. Consult your doctor.

Important: Ticagrelor may increase your risk of bleeding. Do not take this medication if you have active bleeding, a history of bleeding in the brain, or other bleeding disorders.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of the Ticagrelor 90 mg Tablet IP?

It is used to prevent heart attacks and strokes in patients at high risk, especially those with acute coronary syndrome or coronary stents.

Can taking the Ticagrelor 90 mg Tablet IP increase the risk of bleeding?

Yes, taking Ticagrelor 90 mg Tablet IP can increase the risk of bleeding. So, please be very cautious while cutting fingernails or toenails, shaving, or using sharp objects to avoid bleeding.

Does Ticagrelor 90 mg Tablet IP need to be discontinued before undergoing surgery?

Please consult your doctor if the Ticagrelor 90 mg Tablet IP needs to be stopped before undergoing surgery. The doctor might ask you to stop taking it a few days before surgery since it can cause an increased risk of bleeding during surgery.

Can I take herbal supplements with the Ticagrelor 90 mg Tablet IP?

There might be a problem if you take herbal therapies with Ticagrelor 90 mg Tablet IP, especially those that affect blood, like Ginkgo Biloba, grapefruit, or St John's wort (an antidepressant). Taking these together can increase your risk of bleeding. Tell your doctor if you are using any herbal supplements before starting the Ticagrelor 90 mg Tablet IP.

Is Ticagrelor 90 mg Tablet IP safe for patients with asthma?

No, Ticagrelor 90 mg Tablet IP may make it harder to breathe. Consult your doctor if the problem persists, as he/she may adjust the dose or prescribe an alternative medicine.

Is there some kind of food or drink that I need to avoid?

Do not drink grapefruit juice while taking the Ticagrelor 90 mg Tablet IP. Grapefruit juice may increase the blood-thinning effect of the medicine.

Can I take Clopidogrel and Ticagrelor 90 mg Tablet IP together?

Ticagrelor 90 mg Tablet IP contains ticagrelor, which, when taken with clopidogrel, may increase the risk of bleeding. Consult the doctor before taking other medicines with the Ticagrelor 90 mg Tablet IP.

Can I stop taking Ticagrelor 90 mg Tablet IP?

Ticagrelor 90 mg Tablet IP should not be discontinued without a doctor's consultation. Stopping it might increase the risk of a heart attack or stroke.

Can Ticagrelor 90 mg Tablet IP cause blood in urine?

Yes, Ticagrelor 90 mg Tablet IP may cause blood in urine. Consult the doctor if you experience this.

Will Ticagrelor 90 mg Tablet IP lower the blood pressure?

Ticagrelor 90 mg Tablet IP might lower blood pressure. Let the doctor know if you are taking anti-hypertensives (blood pressure-lowering medicines). Regular monitoring of blood pressure levels is advised.

Can I take Ticagrelor 90 mg Tablet IP if I am taking other medicines?

Ticagrelor 90 mg Tablet IP can be taken with other medicines if prescribed by the doctor. Before starting it, inform the doctor if you are taking any other medicines to prevent interactions.

Is Ticagrelor 90 mg Tablet IP an anticoagulant?

No, Ticagrelor 90 mg Tablet IP is an antiplatelet medicine that inhibits the aggregation of platelets that may cause a heart attack or stroke.

Can I drink alcohol with the Ticagrelor 90 mg Tablet IP?

Limit alcohol consumption with Ticagrelor 90 mg Tablet IP, as it might increase the risk of bleeding.

What is the most important thing I should know about Ticagrelor 90 mg Tablet IP?

Ticagrelor 90 mg Tablet IP may cause significant, sometimes fatal bleeding. Inform the doctor if you have/had a condition that causes you to bleed more easily than normal; bleeding in your stomach, intestines, or brain; a stomach ulcer; polyps (abnormal growths in the lining of the large intestine); a stroke or mini-stroke; or liver disease. Seek immediate medical attention if you experience unexplained, severe, long-lasting, or uncontrollable bleeding; red or black, tarry stools; pink or brown urine; vomit that is bloody or that looks like coffee grounds; or coughing up blood or blood clots.