Product Description

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP is used as an adjunct therapy to prevent angina pectoris (chest pain caused by coronary artery disease) in adult patients, usually in combination with other medications. Angina occurs when the heart muscle does not receive enough oxygen due to narrowed or blocked blood vessels.

Trimetazidine is a metabolic agent that improves the heart’s efficiency by shifting energy metabolism from fatty acid oxidation to glucose oxidation, which requires less oxygen. This helps the heart function better under oxygen-limited conditions.

It is also sometimes used off-label for vertigo, tinnitus, and certain visual disturbances, but these uses should be discussed with your doctor.

Uses

Prevention of angina pectoris attacks (adjunct therapy)

How it works

Trimetazidine reduces the heart’s oxygen requirement by optimizing energy metabolism, shifting it from fatty acid to glucose oxidation, which is more oxygen-efficient. This helps improve heart function during ischemic episodes. Additionally, it is used to treat vertigo (a spinning sensation), tinnitus (ringing in the ears), and reduced vision or visual field disturbances (blurred or impaired vision).

Benefits

By improving myocardial metabolism, Trimetazidine helps reduce the frequency and severity of angina attacks and improves exercise tolerance. 

How to use

Swallow the tablet whole with water. Do not crush, break, or chew it. Take as prescribed by your doctor.

Side Effects

• Dizziness

• Headache

• Diarrhea

• Vomiting

• Indigestion

• Abdominal pain

• Nausea

• Rarely, movement disorders such as Parkinsonian symptoms (especially in elderly patients)

Safety Advice

• Avoid alcohol, as it may increase dizziness.

• Use caution if you have liver or kidney disease; dosage adjustments may be necessary.

• Inform your doctor if you have Parkinson’s disease or other movement disorders, as Trimetazidine may worsen these conditions.

• Report any unusual involuntary movements or muscle stiffness immediately.

If you feel any discomfort, you should speak with a doctor.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

What is the use of Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP?

It is used to prevent angina attacks by improving heart metabolism.

How does Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP work in angina?

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP decreases the body's oxygen requirement by shifting metabolism from fats to glucose, increasing the rate at which glucose is broken down. As a result, the heart functions more efficiently and needs less oxygen.

Can Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP stop acute attacks of angina?

No, it does not relieve sudden angina attacks, but it helps prevent future episodes.

What should I do if I miss a dose of Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP?

In case you have missed a dose of Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both doses together. Take only one dose; taking a double dose of Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP will lead to low blood pressure.

Can Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP be taken for years?
Yes, but only under medical supervision. Do not self-medicate for extended periods.

If I feel better, can I stop taking Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP?

No, Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP should not be stopped even if you feel better, as it worsens your condition. If you start to feel better, you should still consult your doctor before making any changes to your medication.

Do Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP cause drowsiness?

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP may cause drowsiness. If you experience excessive sleepiness, consult your doctor for further guidance.

Is Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP recommended for elderly patients?

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP should be used with caution in elderly patients. Please consult the doctor before using Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP before using Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP in geriatric patients.

Can children take Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP?

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP is not recommended for use in children. Please consult the doctor if you have any concerns.

Do Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP cause weight gain?

No, Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP may not cause weight gain. Maintain a healthy diet and regular exercise routine to achieve and sustain a healthy weight.

Is Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP a beta blocker?

No, Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP is not a beta blocker. It is an anti-anginal medicine.

Who should not take Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP?

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP should not be taken by people who are allergic to any of its components. Inform the doctor if you have severe kidney disease or Parkinson's disease.

Does taking Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP increase the risk of falling frequently?

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP might increase the risk of falling due to a drop in blood pressure or instability while walking. Be cautious while getting up from a sitting/lying position.

How should Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP be taken?

Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP should be swallowed as a whole with water; do not crush or chew it.

What are the possible side effects of Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP?

The possible side effects of Trimetazidine Hydrochloride Modified Release Tablets 35 mg IP are dizziness, headache, diarrhoea, vomiting, indigestion, abdominal pain, and feeling sick.