Product Description

Vildagliptin 100 mg, Dapagliflozin 10 mg & Metformin 1000 mg Tablets IP is a fixed-dose triple combination oral antidiabetic medication used in the management of type 2 diabetes mellitus (T2DM) in adults. This combination integrates three complementary antidiabetic agents—vildagliptin (a DPP-4 inhibitor), dapagliflozin (an SGLT2 inhibitor), and metformin (a biguanide)—to provide effective and comprehensive glycemic control.

Type 2 diabetes mellitus is a chronic metabolic disorder characterized by insulin resistance, impaired insulin secretion, and increased hepatic glucose production. This triple therapy is indicated in patients whose blood glucose levels are inadequately controlled with metformin alone or dual-combination therapy, and it should be used along with diet and exercise.

Uses

• Improvement of glycemic control in adults with type 2 diabetes mellitus
  

• Management of hyperglycemia in patients not adequately controlled on dual therapy or metformin monotherapy
  

• Adjunct to diet and lifestyle modifications for better blood sugar control
  

Not indicated for type 1 diabetes mellitus or diabetic ketoacidosis.

How it Works

Vildagliptin 100 mg, Dapagliflozin 10 mg & Metformin 1000 mg Tablets IP act through three complementary mechanisms:

Vildagliptin (100 mg): A dipeptidyl peptidase-4 (DPP-4) inhibitor that increases endogenous incretin levels, enhancing glucose-dependent insulin secretion and reducing glucagon release, thereby lowering postprandial blood glucose levels.

Dapagliflozin (10 mg): A sodium-glucose cotransporter-2 (SGLT2) inhibitor that promotes urinary excretion of excess glucose by inhibiting glucose reabsorption in the kidneys, resulting in reduced blood glucose levels independent of insulin.

Metformin (1000 mg): Reduces hepatic glucose production, improves peripheral insulin sensitivity, and enhances glucose uptake by muscles, leading to improved fasting and postprandial glycemic control.

Together, these mechanisms help lower blood glucose levels and improve overall glycemic control.

Benefits

• Provides comprehensive blood sugar control through three complementary pathways
  

• Reduces both fasting and post-meal blood glucose levels
  

• Helps lower HbA1c levels effectively
  

• Supports weight management due to glucose excretion via urine
  

• Low risk of hypoglycemia when used alone
  

• Improves long-term glycemic control when combined with diet and exercise
  

How to Use

Take Vildagliptin 100 mg, Dapagliflozin 10 mg & Metformin 1000 mg Tablets IP exactly as prescribed by your doctor.

• Swallow the tablet whole with a glass of water
  

• Do not crush, chew, or break the tablet
  

• Can be taken with meals to reduce gastrointestinal side effects
  

• Take the tablet at the same time each day for optimal effectiveness
  

Regular monitoring of blood glucose levels is advised.

Side Effects

Common side effects may include:

• Nausea
  

• Diarrhea
  

• Stomach upset or abdominal pain
  

• Headache
  

• Fatigue
  

• Increased urination
  

• Genital or urinary tract infections
  

Consult your doctor if side effects persist or worsen.

Safety Advice

• Inform your doctor if you have kidney disease, liver disease, heart problems, or a history of pancreatitis
  

• Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis
  

• Maintain adequate hydration while taking this medication
  

• Not recommended during pregnancy or breastfeeding unless advised by a doctor
  

• Not suitable for patients with type 1 diabetes or diabetic ketoacidosis
  

• Inform your doctor about all other medicines you are taking to avoid interactions
  

Storage Conditions

• Store below 30°C (86°F)
  

• Protect from light and moisture
  

• Keep out of reach of children
  

FAQs

What is the use of Vildagliptin 100 mg, Dapagliflozin 10 mg & Metformin 1000 mg Tablets IP?

It is used to control blood sugar levels in adults with type 2 diabetes mellitus when diet, exercise, and other medicines are insufficient.

Does this medicine cure diabetes?

No. It helps manage blood sugar levels but does not cure diabetes.

Can this medicine cause low blood sugar?

The risk is low when used alone, but it may increase if combined with insulin or sulfonylureas.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not take a double dose.

Can I stop taking this medicine once my sugar levels are controlled?

Do not stop taking the medicine without consulting your doctor, as blood sugar levels may rise again.

Is this medicine safe for long-term use?

Yes, when taken as prescribed and monitored regularly by a healthcare professional.