Product Description

Vildagliptin Tablets IP 100mg is a prescription anti-diabetic medication from the dipeptidyl peptidase-4 (DPP-4) inhibitor class, used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is particularly effective when diet, exercise, and other therapies are insufficient. Type 2 diabetes occurs when the body resists insulin or produces insufficient amounts, leading to elevated blood glucose and potential complications like heart disease or nerve damage. This tablet helps by enhancing the body's natural incretin hormones, which stimulate insulin release.

Uses

• Management of type 2 diabetes mellitus in adults, to lower blood glucose levels when lifestyle changes and other oral antidiabetics are inadequate.

• Adjunctive therapy to improve glycemic control and reduce the risk of diabetes-related complications, such as cardiovascular events or nephropathy.

How it works

Vildagliptin Tablets IP 100mg contains Vildagliptin, a DPP-4 inhibitor that prevents the breakdown of incretin hormones (e.g., GLP-1 and GIP). These hormones are released after meals and stimulate insulin secretion from the pancreas while suppressing glucagon release from the liver. By prolonging incretin activity, Vildagliptin enhances glucose-dependent insulin release, lowers fasting and post-meal blood sugar, and improves overall glycemic control without increasing hypoglycemia risk. The onset of action is within 1–2 hours, with effects lasting up to 24 hours.

Benefits

• Effective blood sugar control: Reduces HbA1c by 0.5–1% in clinical trials (e.g., from the Diabetes, Obesity and Metabolism journal), improving insulin sensitivity and minimizing post-meal spikes.

• Low hypoglycemia risk: Works in a glucose-dependent manner, making it safer for long-term use compared to some sulfonylureas.

• Complementary therapy: Can be combined with other antidiabetics for enhanced efficacy, with studies showing better outcomes in patients with uncontrolled diabetes.

How to use

Take Vildagliptin Tablets IP 100mg with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Side Effects

Common side effects (usually mild and transient):

• Gastrointestinal: Nausea, stomach pain, or diarrhea.

• Other: Headache, dizziness, or upper respiratory tract infection.

Rare but serious side effects may include pancreatitis, severe allergic reactions, or liver issues. Consult a doctor if side effects persist.

Safety Advice

• Alcohol Interaction: Avoid alcohol, as it can increase the risk of pancreatitis and hypoglycemia.

• Pregnancy and Breastfeeding: Classified as Pregnancy Category B (no clear evidence of risk in humans), so use only if the benefits outweigh risks. It may pass into breast milk; consult your doctor if pregnant or breastfeeding.

• Other Precautions: Use with caution in patients with kidney or liver impairment, as dose adjustments are needed. Monitor for hypoglycemia, especially when combined with other antidiabetics. Inform your doctor of all medications to avoid interactions (e.g., with insulin or sulfonylureas). Not suitable for type 1 diabetes or diabetic ketoacidosis. Regular blood tests (e.g., for kidney function) are advised.

• Lifestyle Advice: Follow a balanced diet, exercise regularly, and monitor blood sugar. Do not drive if experiencing dizziness.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

Can I take Vildagliptin Tablets IP 100mg with metformin?

Yes, you may take Vildagliptin Tablets IP 100mg with metformin. However, please consult a doctor before using Vildagliptin Tablets IP 100mg with other medicines so that the dose may be adjusted appropriately.

Is Vildagliptin Tablets IP 100mg safe for patients suffering from pancreatitis?

Vildagliptin Tablets IP 100mg should be used with extreme caution in patients suffering from or who have a history of pancreatitis (swelling of the pancreas), as it may increase the risk of recurrent pancreatitis or worsen the condition. However, if you experience any symptoms such as vomiting, stomach pain, or nausea, consult a doctor immediately.

Do Vildagliptin Tablets IP 100mg cause low blood sugar levels?

Vildagliptin Tablets IP 100mg alone does not cause low blood sugar levels. However, low blood sugar levels may occur if Vildagliptin Tablets IP 100mg is taken along with other antidiabetic medicines, alcohol intake, exercise more than usual, delay or miss snacks or meals. However, if you experience any signs of low blood pressure, such as dizziness, nausea, light-headedness, dehydration, or fainting, please consult a doctor.

Can I stop taking Vildagliptin Tablets IP 100mg on my own?

No, you are not recommended to stop taking Vildagliptin Tablets IP 100mg on your own, as discontinuing Vildagliptin Tablets IP 100mg suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Vildagliptin Tablets IP 100mg, please consult your doctor so that alternative medicine may be prescribed.

Does diabetes cause skin lesions?

Yes, diabetic skin lesions are common complications of diabetes. However, you are recommended to follow instructions for foot and skincare as advised by your doctor, and if you notice the onset of any new ulcers or blisters while taking Vildagliptin Tablets IP 100mg, please consult a doctor.

What other lifestyle modifications do I need to consider to manage diabetes?

Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.

What is hypoglycaemia?

Hypoglycaemia is a condition in which the blood sugar/glucose levels are lower than normal.

What are the signs and symptoms of hypoglycaemia?

Symptoms of hypoglycaemia include cold sweat, headache, rapid heartbeat, feeling sick, drowsiness, unusual tiredness, and weakness.

How many tablets of Vildagliptin Tablets IP 100mg can I take in a day?

Your doctor will determine the number of tablets to be taken based on your condition. Please consult the doctor.

When should I take Vildagliptin Tablets IP 100mg?

Vildagliptin Tablets IP 100mg should be taken as prescribed by the doctor. Talk to the doctor if you have any concerns.

Do Vildagliptin Tablets IP 100mg cause weight gain?

Vildagliptin Tablets IP 100mg does not cause weight gain. It is weight-neutral when administered as a monotherapy.

Is Vildagliptin Tablets IP 100mg the same as sitagliptin?

Vildagliptin Tablets IP 100mg contain vildagliptin. Though vildagliptin and sitagliptin both belong to the class of anti-diabetic drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, vildagliptin is not the same as sitagliptin.

What are the side effects of Vildagliptin Tablets IP 100mg?

Side effects of Vildagliptin Tablets IP 100mg are dizziness, nausea, headache, excessive sweating, low blood sugar levels, and trembling. Most of these side effects may not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.