Product Description

Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP is a combination drug containing Vildagliptin (a DPP-4 inhibitor) and Metformin (a biguanide), both belonging to the class of anti-diabetics.

It is used for type 2 diabetes mellitus, previously known as non-insulin-dependent diabetes mellitus (NIDDM) or maturity-onset diabetes.

Type 2 diabetes occurs when the body doesn't produce enough insulin, insulin doesn't work effectively, or there's excess glucagon production. Insulin helps lower blood sugar, especially after meals, while glucagon (produced by the pancreas) signals the liver to release sugar, raising blood glucose.

Uses

Treatment of type 2 diabetes mellitus (as monotherapy or in combination with other antidiabetics).

How it works

Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP combines two mechanisms: Vildagliptin inhibits DPP-4, an enzyme that breaks down GLP-1, leading to increased GLP-1 levels. GLP-1 stimulates insulin release and suppresses glucagon secretion, helping control blood sugar. Metformin reduces glucose production by the liver, improves insulin sensitivity in muscles, and decreases intestinal glucose absorption. Together, they lower blood glucose levels without causing significant weight gain.

Benefits

This tablet helps increase insulin production and utilization, reduces excess sugar from the liver, and controls blood sugar spikes after meals. It aids in managing type 2 diabetes and may help reduce the risk of complications like diabetic retinopathy (eye damage), nephropathy (kidney damage), neuropathy (nerve damage), foot ulcers, and delayed wound healing. Additional benefits include minimal impact on weight and potential cardiovascular protection. Effectiveness depends on diet, exercise, and adherence.

How to use

Swallow it as a whole with water; do not crush, break, or chew it. Take with meals as advised by your doctor to minimise stomach upset. Dosage varies (e.g., 1 tablet daily); follow your prescription exactly.

Side Effects

• Common: Low blood sugar (hypoglycemia), nausea, headache, shaking, vomiting, diarrhea, abdominal pain, loss of appetite, joint pain, tiredness, constipation, swollen hands/ankles/feet (edema).

• Rare but serious: Lactic acidosis (muscle pain, difficulty breathing), pancreatitis, severe allergic reactions (rash, swelling). Contact a doctor if severe or persistent.

Safety Advice

• It is best to avoid alcohol while taking this medication, as it may increase the risk of low blood sugar or lactic acidosis.

• Consult your doctor before use, especially if you have or had liver-related diseases, kidney impairment, heart failure, or are pregnant/breastfeeding.

• Not recommended for severe renal disease or during pregnancy (potential risk to fetus).

• Inform your doctor about all medications (e.g., insulin, diuretics) to avoid interactions.

• Monitor blood sugar, kidney function, and vitamin B12 levels regularly.

Storage Conditions

Store at a temperature below 86°F (30 °C). Protect from light and moisture.

FAQs

How will I know that I am suffering from diabetes?

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact a doctor as it can be a condition of type 2 diabetes.

If my blood sugar level suddenly goes down, then what should I do?

In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.

Is Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP also prescribed for the treatment of type 1 diabetes?

No. Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP is only prescribed for the treatment of type 2 diabetes, also called 'non-insulin-dependent diabetes'.

What is type 2 diabetes, and what are its symptoms and complications?

Type 2 diabetes is a common form of diabetes in which the blood sugar-lowering hormone called insulin, produced by the body, does not function properly. Due to this, the blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger start. Diabetes, if left untreated or not treated properly, can cause long-term complications such as nerve damage, kidney damage, eye damage, foot problems, and also poses a high risk of developing heart diseases.

How long do I need to take Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP?

Continue taking your medicine for as long as your doctor tells you to. Your doctor will check your progress to make sure the medicine is working and will discuss with you how long your treatment should continue. Do not stop taking Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP unless your doctor tells you to.

What diet must I follow?

Include a diet rich in fruits, vegetables, and whole grains like brown rice, whole wheat, oats, barley, and quinoa. Non-fat or low-fat dairy and proteins like chicken, lean meats, nuts, beans, tofu, lentils, eggs, fish, and turkey can also be included.

Can I stop taking Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP?

Do not stop taking Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP on your own, as it might cause an increase in blood sugar levels. Consult the doctor if you have any difficulty while taking the medicine.

What is the best time to take Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP?

Take Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP as advised by the doctor. It can be taken in the morning and evening with or just after food. Taking Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP with food helps lower the risk of stomach upset.

Can the use of Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP lead to hypoglycaemia?

Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP may cause hypoglycaemia (low blood glucose levels), which is characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth, and skin. Regularly monitor blood glucose levels and consume glucose tablets, juice or candy if you experience these symptoms.

Can the use of Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP cause nausea and vomiting?

Vildagliptin 50 mg & Metformin 1000 mg SR Tablet IP may cause side effects such as nausea and vomiting. If you experience these symptoms, eat smaller meals more often and avoid hard-to-digest food. Take small, frequent sips of water or any other fluids. Consult the doctor if the condition persists or worsens.